Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.46 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.42 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.42 |
| ▸ | TFEB | P19484 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3717231 | 1.00 | AR (0.46) | ARPTGES2ALDH1A1NFE2L2IRAK4 | |
| SCHEMBL1073158 | 1.00 | AR (0.46) | ARPTGES2ALDH1A1NFE2L2IRAK4 | |
| SCHEMBL13988354 | 0.90 | AR (0.49) | ARPTGES2ALDH1A1NFE2L2IRAK4 | |
| SCHEMBL5412728 | 0.83 | ALDH1A1 (0.44) | ARPTGES2ALDH1A1NFE2L2IRAK4 | |
| SCHEMBL18441111 | 0.82 | L3MBTL1 (0.46) | PTGES2ALDH1A1NFE2L2MEN1KMT2A | |
| SCHEMBL28781436 | 0.81 | NFE2L2 (0.65) | ARPTGES2NFE2L2TRPA1CYP1A2 | |
| SCHEMBL23841293 | 0.79 | AR (0.43) | ARPTGES2ALDH1A1NFE2L2IRAK4 | |
| SCHEMBL11939336 | 0.79 | KMT2A (0.58) | ARNFE2L2TFEBMEN1KMT2A | |
| SCHEMBL14672769 | 0.79 | KDM4E (0.45) | ARALDH1A1NFE2L2TFEBMEN1 | |
| SCHEMBL2314005 | 0.79 | KDM4E (0.45) | ARALDH1A1NFE2L2TFEBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1455937-B1 | CHELATING CARBENE LIGAND PRECURSORS AND THEIR USE IN THE SYNTHESIS OF METATHESIS CATALYSTS | MATERIA INC (US) | 2018-04-11 | — | — | EP | claimed |
| US-7268242-B2 | Contacting a metathesis-active metal carbene complex with an internal olefin ligand precursors followed by crystallization from an organic solvent | MATERIA, INC. (US) | 2007-09-11 | — | — | US | claimed |
| US-7026495-B1 | Using beta-substituted styrenes instead of terminal olefin compounds such as unsubstituted styrenes to react with a ruthenium complex;recovered and reused; oxidation resistance; storage stability; efficiency; polymerization; cuprous chloride-free and nontoxic; materials handling | MATERIA, INC. (US) | 2006-04-11 | — | — | US | claimed |
| US-11794179-B2 | Synthesis and characterization of metathesis catalysts | UMICORE AG & CO. KG | 2023-10-24 | — | — | US | disclosed |
| US-11779912-B2 | Synthesis and characterization of Ru alkylidene complexes | UMICORE AG & CO. KG (DE) | 2023-10-10 | — | — | US | disclosed |
| EP-4194092-A1 | SYNTHESIS AND CHARACTERIZATION OF METATHESIS CATALYSTS | Umicore AG & Co. KG (DE) | 2023-06-14 | — | — | EP | disclosed |
| US-20230172051-A1 | ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DEVICE HAVING THEREOF | LG DISPLAY CO., LTD. (KR) | 2023-06-01 | — | — | US | disclosed |
| US-20220209140-A1 | ORGANIC METAL COMPOUND, ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DEVICE HAVING THE COMPOUND | LG DISPLAY CO., LTD. (KR) | 2022-06-30 | — | — | US | disclosed |
| US-20210394167-A1 | SYNTHESIS AND CHARACTERIZATION OF RU ALKYLIDENE COMPLEXES | UMICORE AG & CO. KG (DE) | 2021-12-23 | — | — | US | disclosed |
| US-11192911-B2 | Process for producing ruthenium complexes and intermediates thereof and their use in olefin metathesis | APEIRON SYNTHESIS S.A. (PL) | 2021-12-07 | — | — | US | disclosed |
| US-11123722-B2 | Synthesis and characterization of Ru alkylidene complexes | UMICORE AG & CO. KG | 2021-09-21 | — | — | US | disclosed |
| US-7268242-B2 | Contacting a metathesis-active metal carbene complex with an internal olefin ligand precursors followed by crystallization from an organic solvent | MATERIA, INC. (US) | 2007-09-11 | — | — | US | disclosed |
| WO-2007075427-A1 | ORGANOMETALLIC RUTHENIUM COMPLEXES AND RELATED METHODS FOR THE PREPARATION OF TETRA-SUBSTITUTED AND OTHER HINDERED OLEFINS | MATERIA, INC. (US) | 2007-07-05 | — | — | WO | disclosed |
| US-20060122412-A1 | Contacting a metathesis-active metal carbene complex with an internal olefin ligand precursors followed by crystallization from an organic solvent | MATERIA, INC. (US) | 2006-06-08 | — | — | US | disclosed |
| US-7026495-B1 | Using beta-substituted styrenes instead of terminal olefin compounds such as unsubstituted styrenes to react with a ruthenium complex;recovered and reused; oxidation resistance; storage stability; efficiency; polymerization; cuprous chloride-free and nontoxic; materials handling | MATERIA, INC. (US) | 2006-04-11 | — | — | US | disclosed |
| EP-1455937-A4 | CHELATING CARBENE LIGAND PRECURSORS AND THEIR USE IN THE SYNTHESIS OF METATHESIS CATALYSTS | MATERIA INC (US) | 2005-10-19 | — | — | EP | disclosed |
| EP-1455937-A2 | CHELATING CARBENE LIGAND PRECURSORS AND THEIR USE IN THE SYNTHESIS OF METATHESIS CATALYSTS | Materia, Inc. (US) | 2004-09-15 | — | — | EP | disclosed |
| US-6620955-B1 | Complexing group VIII compounds with beta-substituted styrenes, to form stereospecific coordination catalysts used in metathesis ring-opening polymerizations | UMICORE AG & CO. KG (DE) | 2003-09-16 | — | — | US | disclosed |
| US-20030166955-A1 | Polymerization catalyst for alpha-olefins | UMICORE AG & CO. KG (DE) | 2003-09-04 | — | — | US | disclosed |
| WO-2003044060-A2 | CHELATING CARBENE LIGAND PRECURSORS AND THEIR USE IN THE SYNTHESIS OF METATHESIS CATALYSTS | MATERIA, INC. (US) | 2003-05-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060122412-A1 | Contacting a metathesis-active metal carbene complex with an internal olefin ligand precursors followed by crystallization from an organic solvent | HAO2, SCO2, SOD1 | AR 2167/4885PTGES2 1093/4885ALDH1A1 987/4885 |
| US-11192911-B2 | Process for producing ruthenium complexes and intermediates thereof and their use in olefin metathesis | POR, CYP1B1, CYP4F11 | AR 3045/4885PTGES2 879/4885ALDH1A1 406/4885 |
| US-20210394167-A1 | SYNTHESIS AND CHARACTERIZATION OF RU ALKYLIDENE COMPLEXES | PORCN, ORC3, COASY | AR 1468/4885PTGES2 348/4885ALDH1A1 1478/4885 |
| US-20220209140-A1 | ORGANIC METAL COMPOUND, ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DEVICE HAVING THE COMPOUND | OCIAD1, OLA1, OXA1L | AR 2028/4885PTGES2 2748/4885ALDH1A1 196/4885 |
| US-20030166955-A1 | Polymerization catalyst for alpha-olefins | SOD1, HAO2, SCO2 | AR 2380/4885PTGES2 1115/4885ALDH1A1 481/4885 |
| US-11794179-B2 | Synthesis and characterization of metathesis catalysts | SQLE, FDFT1, FASN | AR 2645/4885PTGES2 117/4885ALDH1A1 1128/4885 |
| US-11779912-B2 | Synthesis and characterization of Ru alkylidene complexes | PORCN, ORC3, COASY | AR 1468/4885PTGES2 348/4885ALDH1A1 1478/4885 |
| US-11123722-B2 | Synthesis and characterization of Ru alkylidene complexes | PORCN, ORC3, COASY | AR 1468/4885PTGES2 348/4885ALDH1A1 1478/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.