Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 8/20 | 0.55 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | CRHBP | P24387 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.44 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10733822 | 0.83 | PRSS1 (0.48) | PRSS1SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL2552417 | 0.79 | MAPT (0.53) | HCAR3PKMMAPTNPC1CRHBP | |
| SCHEMBL7973678 | 0.78 | SMN1; SMN2 (0.62) | HCAR3PRSS1SMN1; SMN2ALDH1A1NPSR1 | |
| SCHEMBL28644813 | 0.78 | KMT2A (0.58) | HCAR3ALDH1A1NPSR1PKMMAPT | |
| SCHEMBL7960520 | 0.77 | SMN1; SMN2 (0.61) | HCAR3PRSS1SMN1; SMN2ALDH1A1NPSR1 | |
| SCHEMBL10502410 | 0.77 | HCAR3 (0.74) | HCAR3ALDH1A1NPSR1MAPTKMT2A | |
| SCHEMBL7972061 | 0.74 | MAPT (0.75) | HCAR3PRSS1SMN1; SMN2ALDH1A1NPSR1 | |
| SCHEMBL1958574 | 0.74 | SMN1; SMN2 (0.62) | HCAR3PRSS1SMN1; SMN2ALDH1A1NPSR1 | |
| SCHEMBL9725429 | 0.73 | PKM (0.65) | HCAR3PRSS1SMN1; SMN2ALDH1A1NPSR1 | |
| SCHEMBL7974178 | 0.73 | ALDH1A1 (0.64) | HCAR3PRSS1SMN1; SMN2ALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4699909-A | CARDIOTONICS, HYPOTENSIVES AND ANTITHROMBOTICS | DR. KARL THOMAE GMBH (DE) | 1987-10-13 | — | — | US | disclosed |
| US-4616018-A | CARDIOTOINC AGENTS, HYPOTENSIVES, AND ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1986-10-07 | — | — | US | disclosed |