Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 15/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9300692 | 0.82 | GSK3A (0.46) | TSHRRAB9AL3MBTL1 | |
| SCHEMBL27339301 | 0.77 | ALDH1A1 (0.49) | TNFTSHRMAPTRAB9AL3MBTL1 | |
| SCHEMBL6190090 | 0.74 | MEN1 (0.44) | TNFCYP1A2KDM4EMAPTRAB9A | |
| SCHEMBL28056771 | 0.74 | L3MBTL1 (0.51) | TNFCYP1A2TSHRRAB9AL3MBTL1 | |
| SCHEMBL7429783 | 0.74 | ALOX15 (0.59) | TNFTSHRKDM4E | |
| SCHEMBL10867514 | 0.73 | CYP1A2 (0.44) | TNFCYP1A2TSHRRAB9AL3MBTL1 | |
| SCHEMBL11210331 | 0.73 | TNF (0.58) | TNFCYP1A2 | |
| SCHEMBL5339766 | 0.72 | TSHR (0.40) | TNFCYP1A2TSHRRAB9AL3MBTL1 | |
| SCHEMBL31188474 | 0.72 | KDM4E (0.42) | TNFCYP1A2KDM4EMAPTRAB9A | |
| SCHEMBL9686747 | 0.72 | L3MBTL1 (0.38) | MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105246473-A | Fe(iii) complex compounds for the treatment and prophylaxis of iron deficiency symptoms and iron deficiency anemia | VIFOR INT AG | 2016-01-13 | — | — | CN | disclosed |
| EP-0245053-A1 | Heterocyclic fused tricyclic compounds | ICI AMERICAS INC. (US) | 1987-11-11 | — | — | EP | disclosed |