Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | TDO2 | P48775 | 1/20 | 0.37 |
| ▸ | IDO2 | Q6ZQW0 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | MPI | P34949 | 1/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.36 |
| ▸ | RHOA | P61586 | 1/20 | 0.35 |
| ▸ | C1R | P00736 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10744909 | 0.87 | IDO1 (0.42) | KMT2AMEN1IDO1TDO2IDO2 | |
| SCHEMBL10748283 | 0.80 | METAP2 (0.36) | KMT2AMEN1IDO1MAPTLMNA | |
| SCHEMBL10744792 | 0.80 | PIK3CG (0.40) | KMT2AMAPTLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL10747393 | 0.80 | METAP2 (0.39) | KMT2AMEN1CYP1A2IDO1MAPT | |
| SCHEMBL10747422 | 0.77 | MEN1 (0.41) | KMT2AMEN1IDO1MAPTLMNA | |
| SCHEMBL10745118 | 0.76 | RAB9A (0.53) | KMT2AMEN1CYP1A2MAPTNPC1 | |
| SCHEMBL10503512 | 0.75 | ALDH1A1 (0.44) | KMT2AMEN1IDO1MAPTNPC1 | |
| SCHEMBL10501312 | 0.74 | MEN1 (0.46) | KMT2AMEN1MAPTLMNAALDH1A1 | |
| SCHEMBL10501265 | 0.74 | MPI (0.49) | KMT2AMEN1MAPTLMNASMN1; SMN2 | |
| SCHEMBL10502143 | 0.74 | METAP2 (0.45) | KMT2AMEN1IDO1TDO2IDO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4711961-A | Benzisoselenazolethiones and process for the treatment of various diseases in humans | A. NATTERMANN & CIE GMBH (DE) | 1987-12-08 | — | — | US | disclosed |
| EP-0154851-A1 | Benzisoselenazolethiones,process for their preparation and pharmaceutical products containing these compounds | A. Nattermann & Cie. GmbH (DE) | 1985-09-18 | — | — | EP | disclosed |