Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | DHFR | P00374 | 2/20 | 0.39 |
| ▸ | CRHR1 | P34998 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CHKA | P35790 | 1/20 | 0.32 |
| ▸ | TERT | O14746 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | S100B | P04271 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL564593 | 0.75 | CYP2A6 (0.46) | CYP1A2CYP2A6TSHRDHFRCRHR1 | |
| SCHEMBL23066756 | 0.75 | CRHR1 (0.46) | DHFRCRHR1KDM4EL3MBTL1CHKA | |
| SCHEMBL249237 | 0.73 | CTDSP1 (0.45) | CYP1A2DHFRKDM4E | |
| SCHEMBL6580919 | 0.71 | S100B (0.62) | TSHRDHFRCRHR1CHKAS100B | |
| SCHEMBL11375051 | 0.71 | CYP1A2 (0.49) | CYP1A2DHFRCRHR1KDM4ETERT | |
| SCHEMBL10935728 | 0.70 | INSR (0.46) | CYP1A2CYP2A6TSHRDHFRKDM4E | |
| SCHEMBL5386689 | 0.70 | TERT (0.58) | DHFRCRHR1MAPTCHKATERT | |
| SCHEMBL851567 | 0.70 | CHKA (0.50) | CYP1A2TSHRDHFRCRHR1L3MBTL1 | |
| SCHEMBL544100 | 0.69 | ALDH1A1 (0.48) | TSHRCRHR1KDM4ECHKASMN1; SMN2 | |
| SCHEMBL11142526 | 0.69 | ALDH1A1 (0.43) | CYP2A6TSHRDHFRCRHR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0228046-A2 | Method of increasing the quantum yield in the oxidation of luminol by peroxide in the presence of peroxidase | Roche Diagnostics GmbH (DE) | 1987-07-08 | — | — | EP | disclosed |