Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.61 |
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Toluene SCHEMBL4248351 | 1.00 | ALDH1A1 (0.61) | ALDH1A1LMNAHSD17B10TSHRMEN1 | |
| Toluene SCHEMBL1996289 | 1.00 | ALDH1A1 (0.61) | ALDH1A1LMNAHSD17B10TSHRMEN1 | |
| Toluene SCHEMBL1532531 | 1.00 | ALDH1A1 (0.61) | ALDH1A1LMNAHSD17B10TSHRMEN1 | |
| Toluene SCHEMBL1159815 | 1.00 | ALDH1A1 (0.61) | ALDH1A1LMNAHSD17B10TSHRMEN1 | |
| Toluene SCHEMBL6346934 | 1.00 | ALDH1A1 (0.61) | ALDH1A1LMNAHSD17B10TSHRMEN1 | |
| Toluene SCHEMBL510300 | 1.00 | ALDH1A1 (0.61) | ALDH1A1LMNAHSD17B10TSHRMEN1 | |
| Toluene SCHEMBL8554033 | 1.00 | ALDH1A1 (0.61) | ALDH1A1LMNAHSD17B10TSHRMEN1 | |
| Toluene SCHEMBL414372 | 1.00 | ALDH1A1 (0.61) | ALDH1A1LMNAHSD17B10TSHRMEN1 | |
| Toluene SCHEMBL21490912 | 1.00 | ALDH1A1 (0.61) | ALDH1A1LMNAHSD17B10TSHRMEN1 | |
| Toluene SCHEMBL856707 | 1.00 | ALDH1A1 (0.61) | ALDH1A1LMNAHSD17B10TSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230263791-A1 | STRUCTURAL ANALOGUES OF METHYLPHENIDATE AS PARKINSON'S DISEASE-MODIFYING AGENTS | UNIVERSITA' DEGLI STUDI DI MILANO (IT) | 2023-08-24 | — | — | US | disclosed |
| CN-113088101-B | Polymerizable dichroic dyes | 罗利克技术有限公司 | 2023-07-04 | — | — | CN | disclosed |
| EP-4192456-A1 | STRUCTURAL ANALOGUES OF METHYLPHENIDATE AS PARKINSON'S DISEASE-MODIFYING AGENTS | Universita' degli studi di Brescia (IT) | 2023-06-14 | — | — | EP | disclosed |
| US-20230090208-A1 | 4H-Imidazo[1,2-a]imidazoles for Electronic Applications | UDC IRELAND LTD (IE) | 2023-03-23 | — | — | US | disclosed |
| CN-114315840-A | 4H-imidazo [1,2-a ] imidazoles for electronic applications | UDC 爱尔兰有限责任公司 | 2022-04-12 | — | — | CN | disclosed |
| CN-106188065-B | 4H-imidazo [1,2-a ] imidazoles for electronic applications | UDC 爱尔兰有限责任公司 | 2021-12-28 | — | — | CN | disclosed |
| CN-113088101-A | Polymerizable dichroic dyes | 罗利克技术有限公司 | 2021-07-09 | — | — | CN | disclosed |
| EP-3651225-A1 | NOVEL ORGANIC COMPOUNDS AND AN ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING THE SAME | Idemitsu Kosan Co., Ltd. (JP) | 2020-05-13 | — | — | EP | disclosed |
| EP-3640252-A1 | 4H-IMIDAZO[1,2-A]IMIDAZOLES FOR ELECTRONIC APPLICATIONS | UDC Ireland Limited (IE) | 2020-04-22 | — | — | EP | disclosed |
| US-10431750-B2 | 4H-imidazo[1,2-a]imidazoles for electronic applications | UDC IRELAND LIMITED (IE) | 2019-10-01 | — | — | US | disclosed |
| EP-0871606-B1 | NEW COMPOUNDS AND THEIR COMPOSITIONS HAVING ANTI-INFLAMMATORY AND ANTI-THROMBOTIC ACTIVITIES | NICOX SA (FR) | 2000-06-14 | — | — | EP | disclosed |
| WO-2000031030-A1 | BIFUNCTIONAL PHOTOINITIATORS SUITABLE FOR PHOTOPOLYMERIZATION AND PHOTOPOLYMERIZABLE SYSTEMS CONTAINING THE SAME | LAMBERTI S.P.A. (IT) | 2000-06-02 | — | — | WO | disclosed |
| US-6040341-A | NITRATES; INHIBITORS OF CYCLO-OXYGENASE | NICOX S.A. (FR) | 2000-03-21 | — | — | US | disclosed |
| EP-0759899-B1 | NITRO COMPOUNDS AND THEIR COMPOSITIONS HAVING ANTI-INFLAMMATORY, ANALGESIC AND ANTI-THROMBOTIC ACITIVITIES | NICOX SA (FR) | 1999-09-15 | — | — | EP | disclosed |
| US-5861426-A | NITRO ESTERS OF AROMATIC COMPOUNDS WITH AMIDE OR ESTER GROUPS | NICOX S.A. (FR) | 1999-01-19 | — | — | US | disclosed |
| US-5859006-A | CYCLIZATION; AMIDATION; SELECTIVE INHIBITOR OF CYCLIC GUANOSINE 3',5'-MONOPHOSPHATASE SPECIFIC PHOSPHODIESTERASE; USEFUL IN THE TREATMENT OF CARDIOVASCULAR DISORDERS; TADALAFIL CLAIMED | ICOS CORPORATION (US) | 1999-01-12 | — | — | US | disclosed |
| EP-0759899-A1 | NITRO COMPOUNDS AND THEIR COMPOSITIONS HAVING ANTI-INFLAMMATORY, ANALGESIC AND ANTI-THROMBOTIC ACITIVITIES | NICOX S.A. (FR) | 1997-03-05 | — | — | EP | disclosed |
| WO-1995030641-A1 | NITRO COMPOUNDS AND THEIR COMPOSITIONS HAVING ANTI-INFLAMMATORY, ANALGESIC AND ANTI-THROMBOTIC ACITIVITIES | NICOX S.A. (FR) | 1995-11-16 | — | — | WO | disclosed |
| US-5112851-A | Agricultural Fungicides | SANDOZ LTD. (CH) | 1992-05-12 | — | — | US | disclosed |
| US-4339450-A | CARDIOVASCULAR DISORDERS, ANTIARRHYTHMIA AGENTS | SANOFI (FR) | 1982-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10431750-B2 | 4H-imidazo[1,2-a]imidazoles for electronic applications | EIF4A1, ITPR2, ITPR1 | ALDH1A1 355/4885LMNA 3640/4885HSD17B10 4691/4885 |
| US-20230090208-A1 | 4H-Imidazo[1,2-a]imidazoles for Electronic Applications | PAH, NISCH, KCNH1 | ALDH1A1 405/4885LMNA 3528/4885HSD17B10 3615/4885 |
| US-20230263791-A1 | STRUCTURAL ANALOGUES OF METHYLPHENIDATE AS PARKINSON'S DISEASE-MODIFYING AGENTS | SNCA, PARK7, SYNJ1 | ALDH1A1 2340/4885LMNA 3262/4885HSD17B10 4007/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.