Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 6/20 | 0.40 |
| ▸ | NPC1 | O15118 | 5/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.35 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.35 |
| ▸ | HTR3B | O95264 | 1/20 | 0.35 |
| ▸ | HTR3A | P46098 | 1/20 | 0.35 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.35 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12099900 | 0.81 | PKM (0.39) | ALDH1A1NR4A2RAB9ANPC1L3MBTL1 | |
| SCHEMBL12468595 | 0.78 | PARP10 (0.39) | ALDH1A1RAB9ANPC1L3MBTL1PARP10 | |
| SCHEMBL1304403 | 0.77 | MAPT (0.36) | ALDH1A1RAB9ANPC1TDP1 | |
| SCHEMBL5309684 | 0.70 | ALPL (0.44) | ALDH1A1RAB9ANPC1L3MBTL1PPARG | |
| SCHEMBL3667309 | 0.69 | CYP3A4 (0.42) | ALDH1A1RAB9ANPC1L3MBTL1PPARG | |
| SCHEMBL6544667 | 0.68 | ALDH1A1 (0.41) | ALDH1A1RAB9ANPC1PARP10 | |
| SCHEMBL9696386 | 0.65 | BLM (0.49) | ALDH1A1RAB9ANPC1L3MBTL1TDP1 | |
| SCHEMBL27962347 | 0.64 | NPC1 (0.42) | ALDH1A1RAB9ANPC1 | |
| SCHEMBL3561653 | 0.63 | NPC1 (0.75) | ALDH1A1RAB9ANPC1L3MBTL1 | |
| SCHEMBL1019370 | 0.63 | ALOX15 (0.50) | ALDH1A1RAB9ANPC1PPARAPARP10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2269601-A1 | LR-9, LR-74 and LR-90 for use in treating complications resulting from diabetes | City of Hope (US) | 2011-01-05 | — | — | EP | disclosed |