Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAAT3 | P53816 | 4/20 | 0.54 |
| ▸ | PLAAT5 | Q96KN8 | 4/20 | 0.54 |
| ▸ | PLAAT2 | Q9NWW9 | 4/20 | 0.54 |
| ▸ | PLAAT4 | Q9UL19 | 4/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.49 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.49 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.49 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.47 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17142341 | 0.84 | HDAC1 (0.59) | PLAAT3PLAAT5PLAAT2PLAAT4HDAC1 | |
| SCHEMBL27657889 | 0.84 | HDAC3 (0.67) | PLAAT3PLAAT5PLAAT2PLAAT4HDAC1 | |
| Hydroxyphenyl Propionic Acid SCHEMBL10957822 | 0.81 | ESR1 (0.54) | HDAC1HDAC6HDAC3HDAC4HDAC7 | |
| SCHEMBL7328721 | 0.80 | PLAAT3 (0.55) | PLAAT3PLAAT5PLAAT2PLAAT4HDAC1 | |
| Potassium Ion SCHEMBL27717258 | 0.79 | FFAR1 (0.53) | PLAAT3PLAAT5PLAAT2PLAAT4HDAC1 | |
| SCHEMBL7271458 | 0.79 | PLAAT3 (0.59) | PLAAT3PLAAT5PLAAT2PLAAT4HDAC1 | |
| SCHEMBL11240909 | 0.79 | HDAC3 (0.53) | PLAAT3PLAAT5PLAAT2PLAAT4HDAC1 | |
| Phenyl Propionic Acid SCHEMBL5351527 | 0.78 | HDAC1 (0.70) | PLAAT5PLAAT4HDAC1HDAC6HDAC3 | |
| SCHEMBL1154480 | 0.78 | PLAAT3 (0.53) | PLAAT3PLAAT5PLAAT2PLAAT4HDAC1 | |
| SCHEMBL27825386 | 0.78 | PLAAT3 (0.53) | PLAAT3PLAAT5PLAAT2PLAAT4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0123937-B1 | A BASE PRECURSOR FOR HEAT-DEVELOPABLE PHOTOSENSITIVE MATERIAL | FUJI PHOTO FILM CO., LTD. (JP) | 1987-06-10 | — | — | EP | disclosed |
| US-4560763-A | ALKYNYL CARBOXYLIC ACID SALT OF ORGANIC BASE | FUJI PHOTO FILM CO., LTD. (JP) | 1985-12-24 | — | — | US | disclosed |
| EP-0123937-A1 | A base precursor for heat-developable photosensitive material | FUJI PHOTO FILM CO., LTD. (JP) | 1984-11-07 | — | — | EP | disclosed |