Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | CDK4 | P11802 | 1/20 | 0.31 |
| ▸ | CCND1 | P24385 | 1/20 | 0.31 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2096860 | 0.78 | L3MBTL1 (0.50) | ALDH1A1HPGDHTTSMN1; SMN2CHRM2 | |
| SCHEMBL543497 | 0.76 | EPHX1 (0.41) | ALDH1A1HPGDHTTSMN1; SMN2CHRM2 | |
| SCHEMBL188509 | 0.76 | TAAR1 (0.57) | ALDH1A1HPGDHTTCHRM2CHRM1 | |
| SCHEMBL9865979 | 0.76 | PNMT (0.40) | ALDH1A1HPGDHTTSMN1; SMN2CHRM2 | |
| SCHEMBL9881101 | 0.73 | ALDH1A1 (0.42) | ALDH1A1HPGDHTTSMN1; SMN2CDK4 | |
| SCHEMBL11480751 | 0.73 | GABRA1 (0.36) | ALDH1A1HPGDTAAR1L3MBTL1 | |
| SCHEMBL4090048 | 0.73 | L3MBTL1 (0.42) | HPGDSMN1; SMN2CXCL8MAPTNPSR1 | |
| SCHEMBL4090053 | 0.73 | MAPT (0.38) | ALDH1A1HPGDHTTSMN1; SMN2TAAR1 | |
| SCHEMBL910695 | 0.73 | L3MBTL1 (0.59) | ALDH1A1MAPTNPSR1L3MBTL1 | |
| SCHEMBL11801031 | 0.73 | KDM4E (0.47) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4604386-A | CONTROL OF GRAMPOSITIVE BACTERIA | ELI LILLY AND COMPANY (US) | 1986-08-05 | — | — | US | disclosed |
| EP-0168222-A2 | 3-(Alkynylalkyloxy) Cephalosporins | ELI LILLY AND COMPANY (US) | 1986-01-15 | — | — | EP | disclosed |
| EP-0135683-A1 | Method for production of cephalosporin compounds | Takeda Chemical Industries, Ltd. (JP) | 1985-04-03 | — | — | EP | disclosed |
| EP-0074611-A2 | Method for production of cephalosporin compounds | Takeda Chemical Industries, Ltd. (JP) | 1983-03-23 | — | — | EP | disclosed |
| EP-0021676-A1 | 3-Methoxy-2-oxoazetidine derivatives and their production | Takeda Chemical Industries, Ltd. (JP) | 1981-01-07 | — | — | EP | disclosed |