Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL94759 | 0.88 | TSHR (0.48) | TSHR | |
| SCHEMBL27625179 | 0.86 | TSHR (0.46) | TSHR | |
| SCHEMBL7035397 | 0.86 | TSHR (0.46) | TSHR | |
| SCHEMBL27314245 | 0.82 | TSHR (0.42) | TSHR | |
| Cadaverine Tartrate SCHEMBL8321372 | 0.82 | TSHR (0.42) | TSHR | |
| SCHEMBL28182002 | 0.81 | TSHR (0.40) | TSHR | |
| SCHEMBL1864896 | 0.80 | TSHR (0.43) | TSHR | |
| Cadaverine Tartrate SCHEMBL28179966 | 0.79 | TSHR (0.39) | TSHR | |
| SCHEMBL23069532 | 0.77 | ALDH1A1 (0.54) | TSHR | |
| Ammonia Solution, Strong SCHEMBL27726717 | 0.77 | TSHR (0.40) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200080122-A1 | Cleavable Nucleotide Analogs and Uses Thereof | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2020-03-12 | — | — | US | claimed |
| US-20260077088-A1 | SELF-DEGRADING ENZYME LOADED BIOLOGICALLY DERIVED PARTICLES | CRANNMED LIMITED (IE) | 2026-03-19 | — | — | US | disclosed |
| EP-4583839-A1 | SELF-DEGRADING ENZYME LOADED BIOLOGICALLY DERIVED PARTICLES | Crannmed Limited (IE) | 2025-07-16 | — | — | EP | disclosed |
| WO-2025137256-A1 | POLYOXAZOLINE-CARBOHYDRATE-LIPID CONJUGATES | WU NIAN (US) | 2025-06-26 | — | — | WO | disclosed |
| US-20250099480-A1 | METHODS AND PHARMACEUTICAL COMPOSITIONS FOR TREATING CANDIDA AURIS IN BLOOD | CORMEDIX INC (US) | 2025-03-27 | — | — | US | disclosed |
| US-12016865-B2 | Methods and pharmaceutical compositions for treating candida auris in blood | CORMEDIX INC. (US) | 2024-06-25 | — | — | US | disclosed |
| WO-2024052780-A1 | SELF-DEGRADING ENZYME LOADED BIOLOGICALLY DERIVED PARTICLES | CRANNMED LIMITED (IE) | 2024-03-14 | — | — | WO | disclosed |
| US-11712419-B2 | Liposome formulations | OPKO PHARMACEUTICALS, LLC (US) | 2023-08-01 | — | — | US | disclosed |
| US-11458199-B2 | Liposome formulations | OPKO PHARMACEUTICALS, LLC (US) | 2022-10-04 | — | — | US | disclosed |
| EP-2887958-B1 | LIPOSOME FORMULATIONS | OPKO PHARMACEUTICALS LLC (US) | 2021-05-19 | — | — | EP | disclosed |
| US-20120202890-A1 | POLYMER-CARBOHYDRATE-LIPID CONJUGATES | WU NIAN (US) | 2012-08-09 | — | — | US | disclosed |
| US-20120202979-A1 | POLYMER-CARBOHYDRATE-LIPID CONJUGATES | LIPOSEUTICALS, INC. | 2012-08-09 | — | — | US | disclosed |
| WO-2012057628-A2 | CROSS-LINKED POLYMERS AND IMPLANTS DERIVED FROM ELECTROPHILICALLY ACTIVATED POLYOXAZOLINE | BENDER ANALYTICAL HOLDING B.V. (NL) | 2012-05-03 | — | — | WO | disclosed |
| EP-2424971-A1 | METHODS AND COMPOSITIONS FOR MEASURING HIGH AFFINITY INTERACTIONS WITH KINETIC IMAGING OF SINGLE MOLECULE INTERACTION (KISMI) | University of Utah Research Foundation (US) | 2012-03-07 | — | — | EP | disclosed |
| WO-2011139343-A2 | AMINO ACID LINKED PEG-LIPID CONJUGATES | WU NIAN (US) | 2011-11-10 | — | — | WO | disclosed |
| WO-2010127247-A1 | METHODS AND COMPOSITIONS FOR MEASURING HIGH AFFINITY INTERACTIONS WITH KINETIC IMAGING OF SINGLE MOLECULE INTERACTION (KISMI) | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2010-11-04 | — | — | WO | disclosed |
| US-20100076209-A1 | PEG-lipid conjugates for liposomes and drug delivery | BIOZONE LABORATORIES INC. | 2010-03-25 | — | — | US | disclosed |
| US-5045312-A | Complexing | BURROUGHS WELLCOME CO. (US) | 1991-09-03 | — | — | US | disclosed |
| EP-0377649-A1 | HALOGENATED SURFACE WITH REDUCED PROTEIN INTERACTION. | HEWLETT PACKARD CO (US) | 1990-07-18 | — | — | EP | disclosed |
| WO-1989012225-A1 | HALOGENATED SURFACE WITH REDUCED PROTEIN INTERACTION | HEWLETT-PACKARD COMPANY (US) | 1989-12-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100076209-A1 | PEG-lipid conjugates for liposomes and drug delivery | DAGLA, DAGLB, DGKG | TSHR 2520/4885 |
| US-20200080122-A1 | Cleavable Nucleotide Analogs and Uses Thereof | TYMP, DUT, NT5C3B | TSHR 2802/4885 |
| US-20120202890-A1 | POLYMER-CARBOHYDRATE-LIPID CONJUGATES | LIPC, FUT6, UGCG | TSHR 3962/4885 |
| US-20260077088-A1 | SELF-DEGRADING ENZYME LOADED BIOLOGICALLY DERIVED PARTICLES | MMP2, PLG, PMM2 | TSHR 1647/4885 |
| US-20120202979-A1 | POLYMER-CARBOHYDRATE-LIPID CONJUGATES | LIPC, FUT6, UGCG | TSHR 3962/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.