SCHEMBL108725

SCHEMBL108725

CCn1ccc2cc(O)c(O)cc21

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR35 Q9HC97 1/20 0.42
TUBB4A P04350 1/20 0.41
TUBB P07437 1/20 0.41
TUBA3C P0DPH7 1/20 0.41
TUBA1B P68363 1/20 0.41
TUBA4A P68366 1/20 0.41
TUBB4B P68371 1/20 0.41
TUBB3 Q13509 1/20 0.41
TUBB2A Q13885 1/20 0.41
TUBB8 Q3ZCM7 1/20 0.41
TUBA3E Q6PEY2 1/20 0.41
TUBA1A Q71U36 1/20 0.41
TUBA1C Q9BQE3 1/20 0.41
TUBB6 Q9BUF5 1/20 0.41
TUBB2B Q9BVA1 1/20 0.41
TUBB1 Q9H4B7 1/20 0.41
HTR2A P28223 3/20 0.38
HTR2C P28335 3/20 0.38
TNF P01375 1/20 0.38
RORC P51449 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29803617 1.00 GPR35 (0.42) GPR35TUBB4ATUBBTUBA3CTUBA1B
Bromide SCHEMBL4625441 0.98 GPR35 (0.41) GPR35TUBB4ATUBBTUBA3CTUBA1B
Hydrochloric Acid SCHEMBL4625202 0.98 GPR35 (0.41) GPR35TUBB4ATUBBTUBA3CTUBA1B
SCHEMBL6941609 0.91 HTR2A (0.40) GPR35TUBB4ATUBBTUBA3CTUBA1B
SCHEMBL108285 0.85 HTR2A (0.42) GPR35HTR2AHTR2CTNFMTNR1A
SCHEMBL29670034 0.85 HTR2A (0.42) GPR35HTR2AHTR2CTNFMTNR1A
SCHEMBL29915749 0.82 ALDH1A1 (0.43) HTR2AHTR2CTNFMTNR1AMTNR1B
SCHEMBL111621 0.82 ALDH1A1 (0.43) HTR2AHTR2CTNFMTNR1AMTNR1B
Quinoline SCHEMBL27735431 0.81 ALDH1A1 (0.45) CYP19A1MTNR1AKDM4EMEN1MAPT
SCHEMBL1881998 0.79 CDK4 (0.46) HTR2AHTR2CTNFKDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1159 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024205052-A1 COMPOSITION FOR COLORING HAIR 주식회사 엘지생활건강 2024-10-03 WO claimed
WO-2021018445-A1 OXIDANT-FREE METHOD FOR DYEING KERATIN MATERIAL, COMPRISING THE APPLICATION OF AN ORGANIC C1-C6-ALKOXY SILANE AND AN OXIDANT-FREE DYE PRECURSOR HENKEL AG & CO. KGAA (DE) 2021-02-04 WO claimed
CN-103517703-B Stain and application thereof 天野酶制品株式会社 2016-11-09 CN claimed
EP-2623093-B1 DYE FOR KERATIN FIBERS USING BILIRUBIN OXIDASE AND INDOLE DERIVATIVES AMANO ENZYME INC (JP) 2016-05-25 EP claimed
CN-103998016-B Employ the dyeing of the keratin fiber of indole analog AMANO ENZYME INC. (JP) 2015-09-16 CN claimed
US-20140359950-A1 DYEING OF KERATIN FIBERS USING INDOLE ANALOGUE AMANO ENZYME INC. (JP) 2014-12-11 US claimed
EP-2026755-A2 APPLICATION DEVICE FOR USING AN APPLICATION LIQUID ON KERATIN FIBERS Henkel AG & Co. KGaA (DE) 2009-02-25 EP claimed
EP-1286647-B1 OXIDATION DYEING METHOD FOR KERATINOUS FIBERS HENKEL KGAA (DE) 2008-01-09 EP claimed
WO-2007141164-A2 APPLICATION DEVICE FOR USING AN APPLICATION LIQUID ON KERATIN FIBERS HENKEL AG & CO. KGAA (DE) 2007-12-13 WO claimed
EP-1682229-A1 AGENT FOR MINIMISING THE COLORATION OF THE SKIN Henkel Kommanditgesellschaft auf Aktien (DE) 2006-07-26 EP claimed
WO-2004026272-A1 HAIR TREATMENT AGENT HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2004-04-01 WO claimed
US-20030167578-A1 Novel coupling component for oxidative hair dyes HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) 2003-09-11 US claimed
US-20030131425-A1 Containing an indoline, an indole, or a derivative thereof in combination with at least one amino acid or oligopeptide. HOEFFKES HORST (DE) 2003-07-17 US claimed
US-6537330-B1 Indoline hair dye with at least one amino acid or oligopeptide; atmospheric oxygen as the sole oxidizing agent; restores grey hair to its natural color, even originally dark to black hair HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2003-03-25 US claimed
EP-1292266-A2 NOVEL COUPLING COMPONENT FOR OXIDATIVE HAIR DYES Henkel Kommanditgesellschaft auf Aktien (DE) 2003-03-19 EP claimed
EP-1286646-A1 OXIDATION DYEING METHOD FOR KERATINOUS FIBERS Henkel Kommanditgesellschaft auf Aktien (DE) 2003-03-05 EP claimed
EP-1286647-A1 OXIDATION DYEING METHOD FOR KERATINOUS FIBERS Henkel Kommanditgesellschaft auf Aktien (DE) 2003-03-05 EP claimed
WO-2001097756-A2 NOVEL COUPLING COMPONENT FOR OXIDATIVE HAIR DYES HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2001-12-27 WO claimed
WO-2001093819-A1 OXIDATION DYEING METHOD FOR KERATINOUS FIBERS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2001-12-13 WO claimed
WO-2001093818-A1 OXIDATION DYEING METHOD FOR KERATINOUS FIBERS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2001-12-13 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030167578-A1 Novel coupling component for oxidative hair dyes MAOB, CYB5R3, MAOA GPR35 3387/4885TUBB4A 294/4885TUBB 400/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.