SCHEMBL108285

SCHEMBL108285

CCCn1ccc2cc(O)c(O)cc21

nearest known ligand 0.42

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 2/20 0.42
HTR2C P28335 2/20 0.42
DAO P14920 1/20 0.40
TNF P01375 1/20 0.39
TYR P14679 1/20 0.39
CDK4 P11802 3/20 0.38
CCND1 P24385 3/20 0.38
PLG P00747 1/20 0.38
PLAU P00749 1/20 0.38
MTNR1A P48039 3/20 0.38
MTNR1B P49286 3/20 0.38
EGFR P00533 1/20 0.38
KMO O15229 1/20 0.37
GPR35 Q9HC97 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29670034 1.00 HTR2A (0.42) HTR2AHTR2CDAOTNFTYR
SCHEMBL6941609 0.95 HTR2A (0.40) HTR2AHTR2CDAOTNFTYR
SCHEMBL111621 0.89 ALDH1A1 (0.43) HTR2AHTR2CTNFTYRCDK4
SCHEMBL29915749 0.89 ALDH1A1 (0.43) HTR2AHTR2CTNFTYRCDK4
SCHEMBL1881998 0.86 CDK4 (0.46) HTR2AHTR2CTNFCDK4CCND1
SCHEMBL29803617 0.85 GPR35 (0.42) HTR2AHTR2CTNFMTNR1AMTNR1B
SCHEMBL108725 0.85 GPR35 (0.42) HTR2AHTR2CTNFMTNR1AMTNR1B
SCHEMBL8814515 0.83 HTR2A (0.40) HTR2AHTR2CTNFCDK4CCND1
Bromide SCHEMBL4625441 0.83 GPR35 (0.41) HTR2AHTR2CTNFMTNR1AMTNR1B
Hydrochloric Acid SCHEMBL4625202 0.83 GPR35 (0.41) HTR2AHTR2CTNFMTNR1AMTNR1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1116 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021018445-A1 OXIDANT-FREE METHOD FOR DYEING KERATIN MATERIAL, COMPRISING THE APPLICATION OF AN ORGANIC C1-C6-ALKOXY SILANE AND AN OXIDANT-FREE DYE PRECURSOR HENKEL AG & CO. KGAA (DE) 2021-02-04 WO claimed
EP-2026755-A2 APPLICATION DEVICE FOR USING AN APPLICATION LIQUID ON KERATIN FIBERS Henkel AG & Co. KGaA (DE) 2009-02-25 EP claimed
EP-1286647-B1 OXIDATION DYEING METHOD FOR KERATINOUS FIBERS HENKEL KGAA (DE) 2008-01-09 EP claimed
WO-2007141164-A2 APPLICATION DEVICE FOR USING AN APPLICATION LIQUID ON KERATIN FIBERS HENKEL AG & CO. KGAA (DE) 2007-12-13 WO claimed
EP-1682229-A1 AGENT FOR MINIMISING THE COLORATION OF THE SKIN Henkel Kommanditgesellschaft auf Aktien (DE) 2006-07-26 EP claimed
EP-1292266-B1 PYRIDOXINE AS NOVEL COUPLING COMPONENT FOR OXIDATIVE HAIR DYES HENKEL KGAA (DE) 2005-11-16 EP claimed
EP-1536757-A1 HAIR TREATMENT AGENT Henkel Kommanditgesellschaft auf Aktien (DE) 2005-06-08 EP claimed
WO-2005034896-A1 AGENT FOR MINIMISING THE COLORATION OF THE SKIN HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2005-04-21 WO claimed
WO-2004026272-A1 HAIR TREATMENT AGENT HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2004-04-01 WO claimed
US-20030167578-A1 Novel coupling component for oxidative hair dyes HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) 2003-09-11 US claimed
US-20030131425-A1 Containing an indoline, an indole, or a derivative thereof in combination with at least one amino acid or oligopeptide. HOEFFKES HORST (DE) 2003-07-17 US claimed
US-6537330-B1 Indoline hair dye with at least one amino acid or oligopeptide; atmospheric oxygen as the sole oxidizing agent; restores grey hair to its natural color, even originally dark to black hair HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2003-03-25 US claimed
EP-1292266-A2 NOVEL COUPLING COMPONENT FOR OXIDATIVE HAIR DYES Henkel Kommanditgesellschaft auf Aktien (DE) 2003-03-19 EP claimed
EP-1286646-A1 OXIDATION DYEING METHOD FOR KERATINOUS FIBERS Henkel Kommanditgesellschaft auf Aktien (DE) 2003-03-05 EP claimed
EP-1286647-A1 OXIDATION DYEING METHOD FOR KERATINOUS FIBERS Henkel Kommanditgesellschaft auf Aktien (DE) 2003-03-05 EP claimed
WO-2001097756-A2 NOVEL COUPLING COMPONENT FOR OXIDATIVE HAIR DYES HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2001-12-27 WO claimed
WO-2001093818-A1 OXIDATION DYEING METHOD FOR KERATINOUS FIBERS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2001-12-13 WO claimed
WO-2001093819-A1 OXIDATION DYEING METHOD FOR KERATINOUS FIBERS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2001-12-13 WO claimed
US-20260096976-A1 AGENT FOR REPIGMENTATION OF KERATIN FIBERS, IN PARTICULAR HUMAN HAIR DR. KURT WOLFF GMBH & CO. KG (DE) 2026-04-09 US disclosed
WO-1998038175-A1 NOVEL 1,4-DIAZACYCLOHEPTANE DERIVATIVES AND THEIR USE IN HAIR OXIDATION DYES HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1998-09-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030167578-A1 Novel coupling component for oxidative hair dyes MAOB, CYB5R3, MAOA HTR2A 1063/4885HTR2C 1154/4885DAO 184/4885
US-20260096976-A1 AGENT FOR REPIGMENTATION OF KERATIN FIBERS, IN PARTICULAR HUMAN HAIR TYR, KRT18, TPH1 HTR2A 78/4885HTR2C 82/4885DAO 808/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.