Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 4/20 | 0.33 |
| ▸ | DRD2 | P14416 | 3/20 | 0.33 |
| ▸ | HRH2 | P25021 | 2/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.33 |
| ▸ | DRD4 | P21917 | 2/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | HTR1B | P28222 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10891246 | 0.81 | GAA (0.40) | NPC1RAB9ASMN1; SMN2TP53TSHR | |
| Evandamine SCHEMBL6009808 | 0.76 | APOBEC3A (0.42) | ADRA2AADRA2BADRA2CNPC1RAB9A | |
| SCHEMBL13387645 | 0.76 | PDK1 (0.36) | ADRA2AADRA2BADRA2CNPC1RAB9A | |
| SCHEMBL10891333 | 0.75 | TSHR (0.38) | NPC1RAB9ASMN1; SMN2TP53TSHR | |
| SCHEMBL10892079 | 0.72 | SLC27A1 (0.35) | NPC1RAB9ASMN1; SMN2TSHR | |
| SCHEMBL2903952 | 0.69 | RAB9A (0.50) | NPC1RAB9ASMN1; SMN2MITFTP53 | |
| SCHEMBL10888852 | 0.68 | ALDH1A1 (0.31) | NPC1RAB9AMITFTP53 | |
| SCHEMBL10890832 | 0.67 | NPC1 (0.37) | NPC1RAB9ASMN1; SMN2MITFTP53 | |
| Hydrochloric Acid SCHEMBL10891755 | 0.66 | NPC1 (0.36) | ADRA2AADRA2BADRA2CNPC1RAB9A | |
| SCHEMBL10891545 | 0.65 | ALDH1A1 (0.36) | NPC1RAB9ASMN1; SMN2TP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4600722-A | 3-amino-1-(4,5,6,7-tetrahydro-benzothiazolyl)-2-pyrazolines and a process for the treatment of inflammatory or allergic processes in humans | A. NATTERMANN & CIE GMBH (DE) | 1986-07-15 | — | — | US | disclosed |
| EP-0155523-A1 | 3-Amino-1-(4,5,6,7-Tetrahydro-benzothiazolyl)-2-Pyrazolines,a process for their preparation and pharmaceutical products containing these compounds | A. Nattermann & Cie. GmbH (DE) | 1985-09-25 | — | — | EP | disclosed |