Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | TAS2R38 | P59533 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10903651 | 0.82 | USP2 (0.63) | LMNAALDH1A1USP2HSD17B10POLB | |
| SCHEMBL10906136 | 0.75 | LTA4H (0.45) | ALDH1A1GAACYP1A2MAPTHTT | |
| SCHEMBL10905444 | 0.75 | KMT2A (0.46) | ALDH1A1HSD17B10GAAKMT2ACYP1A2 | |
| SCHEMBL10906603 | 0.74 | LTA4H (0.46) | GAAMAPTHTT | |
| SCHEMBL10906184 | 0.71 | MLYCD (0.48) | ALDH1A1USP2HSD17B10POLBHPGD | |
| SCHEMBL10906616 | 0.71 | ALDH1A1 (0.37) | LMNAALDH1A1HPGDGAAKMT2A | |
| SCHEMBL10905453 | 0.70 | MTOR (0.40) | LMNAALDH1A1HSD17B10HPGDGAA | |
| SCHEMBL23618280 | 0.69 | ALDH1A1 (0.61) | ALDH1A1HSD17B10HPGDGAAKMT2A | |
| SCHEMBL5448016 | 0.69 | ALDH1A1 (0.61) | ALDH1A1HSD17B10HPGDGAAKMT2A | |
| SCHEMBL17596668 | 0.68 | MAPT (0.55) | LMNAALDH1A1HSD17B10GAACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4633014-A | ANTIARRHYTHMIA AGENTS | INSTITUT ORGANICHESKOGO SINTEZA AKADEMII NAUK LATVIISKOI SSR | 1986-12-30 | — | — | US | disclosed |