Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | CCR6 | P51684 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NSD2 | O96028 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11221384 | 0.87 | GAA (0.46) | CYP1A2GAAALDH1A1TSHRL3MBTL1 | |
| SCHEMBL11589871 | 0.81 | CYP1A2 (0.48) | CYP1A2GAAALDH1A1TSHRL3MBTL1 | |
| SCHEMBL4272718 | 0.79 | ALDH1A1 (0.56) | CYP1A2GAAALDH1A1TSHRL3MBTL1 | |
| SCHEMBL11527916 | 0.79 | CYP1A2 (0.47) | CYP1A2GAAALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL177202 | 0.78 | CYP1A2 (0.50) | CYP1A2GAAALDH1A1TSHRL3MBTL1 | |
| SCHEMBL10701424 | 0.76 | CYP1A2 (0.48) | CYP1A2GAAALDH1A1TSHRL3MBTL1 | |
| SCHEMBL9555565 | 0.76 | — | — | |
| SCHEMBL22769175 | 0.76 | ALDH1A1 (0.50) | GAAALDH1A1TSHRL3MBTL1SMN1; SMN2 | |
| SCHEMBL28491839 | 0.76 | CYP1A2 (0.48) | CYP1A2GAAALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL10906551 | 0.76 | GAA (0.47) | GAAALDH1A1TSHRL3MBTL1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0594608-B1 | CHIRAL CATALYSTS FOR ENANTIOSELECTIVE SYNTHESIS | RES CORP TECHNOLOGIES INC (US) | 1997-10-15 | — | — | EP | claimed |
| US-10767112-B2 | Methods of producing metal sulfides, metal selenides, and metal sulfides/selenides having controlled architectures using kinetic control | THE TRUSTEES OF THE COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2020-09-08 | — | — | US | disclosed |
| US-10253256-B2 | Use of sulfur and selenium compounds as precursors to nanostructured materials | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2019-04-09 | — | — | US | disclosed |
| US-20170369779-A1 | METHODS OF PRODUCING METAL SULFIDES, METAL SELENIDES, AND METAL SULFIDES/SELENIDES HAVING CONTROLLED ARCHITECTURES USING KINETIC CONTROL | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2017-12-28 | — | — | US | disclosed |
| US-20160237345-A1 | USE OF SULFUR AND SELENIUM COMPOUNDS AS PRECURSORS TO NANOSTRUCTURED MATERIALS | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2016-08-18 | — | — | US | disclosed |
| EP-3049370-A1 | USE OF SULFUR AND SELENIUM COMPOUNDS AS PRECURSORS TO NANOSTRUCTURED MATERIALS | The Trustees of Columbia University in the City of New York (US) | 2016-08-03 | — | — | EP | disclosed |
| US-9114079-B2 | Polymerizable dental material comprising reactive paste formers, hardened dental material and use thereof | KETTENBACH GMBH & CO. KG (DE) | 2015-08-25 | — | — | US | disclosed |
| US-20130225699-A1 | Polymerizable Dental Material Comprising Reactive Paste Formers, Hardened Dental Material and Use Thereof | KETTENBACH GMBH & CO. KG (DE) | 2013-08-29 | — | — | US | disclosed |
| US-20050181421-A1 | Methods of array synthesis | AFFYMETRIX, INC. (US) | 2005-08-18 | — | — | US | disclosed |
| US-6887665-B2 | Forming a surface comprising photosensitive compound or group, an autocatalytic compound or group, compound capable of introducing latency irradiating at least a part of surface to remove protective group | AFFYMETRIX, INC. (US) | 2005-05-03 | — | — | US | disclosed |
| US-20020022721-A1 | Methods of array synthesis | AFFYMETRIX, INC. | 2002-02-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020022721-A1 | Methods of array synthesis | RAC2, RAC3, RAC1 | CYP1A2 1623/4885GAA 2536/4885ALDH1A1 2412/4885 |
| US-20130225699-A1 | Polymerizable Dental Material Comprising Reactive Paste Formers, Hardened Dental Material and Use Thereof | ME1, ME2, ME3 | CYP1A2 3020/4885GAA 2873/4885ALDH1A1 233/4885 |
| US-10253256-B2 | Use of sulfur and selenium compounds as precursors to nanostructured materials | SCLY, TST, SOD1 | CYP1A2 1998/4885GAA 1399/4885ALDH1A1 1898/4885 |
| US-20050181421-A1 | Methods of array synthesis | RAC2, RAC3, RAC1 | CYP1A2 1464/4885GAA 2463/4885ALDH1A1 2290/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.