Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 8/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 2/20 | 0.38 |
| ▸ | CTSK | P43235 | 2/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10936635 | 1.00 | CTSL (0.48) | CTSLEPHX2CTSSCTSKCTSB | |
| SCHEMBL10937584 | 0.87 | CTSL (0.44) | CTSLCTSSCTSKSSTR3NPC1 | |
| SCHEMBL10937589 | 0.87 | CTSL (0.44) | CTSLCTSSCTSKSSTR3NPC1 | |
| SCHEMBL10940237 | 0.86 | ALDH1A1 (0.43) | CTSBNPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL10936648 | 0.86 | OGG1 (0.41) | CTSLCTSSCTSKCTSBNPC1 | |
| SCHEMBL10936654 | 0.86 | OGG1 (0.41) | CTSLCTSSCTSKCTSBNPC1 | |
| SCHEMBL10939773 | 0.86 | FOLH1 (0.37) | CTSLEPHX2 | |
| SCHEMBL10940243 | 0.86 | ALDH1A1 (0.43) | CTSBNPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL10939776 | 0.86 | FOLH1 (0.37) | CTSLEPHX2 | |
| SCHEMBL10935401 | 0.77 | CTSV (0.47) | CTSLCTSSCTSKCTSBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4545942-A | IMMUNOREGULATORS; ANTITUMOR AGENTS | SANKYO COMPANY, LIMITED (JP) | 1985-10-08 | — | — | US | claimed |