Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 3/20 | 0.35 |
| ▸ | TPMT | P51580 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.35 |
| ▸ | GUSB | P08236 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.33 |
| ▸ | DHFR | P00374 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10939776 | 1.00 | FOLH1 (0.37) | FOLH1POLBCTSLTPMTTRPV1 | |
| SCHEMBL10938164 | 0.87 | TRPV1 (0.33) | FOLH1POLBTRPV1GUSBEPHX2 | |
| SCHEMBL10938163 | 0.87 | TRPV1 (0.33) | FOLH1POLBTRPV1GUSBEPHX2 | |
| SCHEMBL10936654 | 0.86 | OGG1 (0.41) | POLBCTSL | |
| SCHEMBL10936639 | 0.86 | CTSL (0.48) | CTSLEPHX2 | |
| SCHEMBL10936635 | 0.86 | CTSL (0.48) | CTSLEPHX2 | |
| SCHEMBL10936648 | 0.86 | OGG1 (0.41) | POLBCTSL | |
| SCHEMBL10940243 | 0.86 | ALDH1A1 (0.43) | POLB | |
| SCHEMBL10940237 | 0.86 | ALDH1A1 (0.43) | POLB | |
| SCHEMBL10935401 | 0.77 | CTSV (0.47) | CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4545942-A | IMMUNOREGULATORS; ANTITUMOR AGENTS | SANKYO COMPANY, LIMITED (JP) | 1985-10-08 | — | — | US | claimed |