Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 2/20 | 0.39 |
| ▸ | FABP2 | P12104 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10940237 | 1.00 | ALDH1A1 (0.43) | ALDH1A1L3MBTL1NPC1MAPK1POLB | |
| SCHEMBL10934472 | 0.87 | MAPK1 (0.42) | ALDH1A1L3MBTL1NPC1MAPK1POLB | |
| SCHEMBL10934466 | 0.87 | MAPK1 (0.42) | ALDH1A1L3MBTL1NPC1MAPK1POLB | |
| SCHEMBL10936654 | 0.86 | OGG1 (0.41) | ALDH1A1NPC1POLBKDM4ELMNA | |
| SCHEMBL10936639 | 0.86 | CTSL (0.48) | ALDH1A1NPC1KDM4EMAPTRAB9A | |
| SCHEMBL10939776 | 0.86 | FOLH1 (0.37) | POLB | |
| SCHEMBL10936648 | 0.86 | OGG1 (0.41) | ALDH1A1NPC1POLBKDM4ELMNA | |
| SCHEMBL10939773 | 0.86 | FOLH1 (0.37) | POLB | |
| SCHEMBL10936635 | 0.86 | CTSL (0.48) | ALDH1A1NPC1KDM4EMAPTRAB9A | |
| SCHEMBL10935401 | 0.85 | CTSV (0.47) | ALDH1A1LMNAMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4545942-A | IMMUNOREGULATORS; ANTITUMOR AGENTS | SANKYO COMPANY, LIMITED (JP) | 1985-10-08 | — | — | US | claimed |
| JP-56147753-A | — | — | None | — | — | JP | disclosed |
| US-4545942-A | IMMUNOREGULATORS; ANTITUMOR AGENTS | SANKYO COMPANY, LIMITED (JP) | 1985-10-08 | — | — | US | disclosed |
| JP-S56147753-A | AMINO ACID DERIVATIVE | SANKYO CO LTD | 1981-11-16 | — | — | JP | disclosed |