Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 4/20 | 0.33 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 4/20 | 0.32 |
| ▸ | RNPEP | Q9H4A4 | 3/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CTSL | P07711 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7716917 | 0.94 | CYP3A4 (0.42) | CYP3A4TSHRNFKB1NPSR1FOLH1 | |
| SCHEMBL11545517 | 0.86 | CYP3A4 (0.39) | CYP3A4TSHRNFKB1NPSR1FOLH1 | |
| SCHEMBL11296153 | 0.80 | — | — | |
| SCHEMBL6738621 | 0.78 | CA1 (0.48) | CYP3A4TSHRNFKB1NPSR1FOLH1 | |
| Silver SCHEMBL6738610 | 0.78 | CA1 (0.48) | CYP3A4TSHRNFKB1NPSR1FOLH1 | |
| Potassium Ion SCHEMBL637500 | 0.77 | CA4 (0.48) | CA4FAHD1CA2CTSL | |
| Potassium Ion SCHEMBL7331283 | 0.77 | — | — | |
| SCHEMBL18207988 | 0.75 | NFKB1 (0.50) | CYP3A4TSHRNFKB1NPSR1CA1 | |
| SCHEMBL3517131 | 0.75 | CYP3A4 (0.34) | CYP3A4TSHRNFKB1NPSR1FOLH1 | |
| SCHEMBL10500712 | 0.75 | CA2 (0.52) | CYP3A4TSHRNFKB1NPSR1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4491627-A | Light-sensitive silver halide photographic material with microcapsules that dissolve at pH of at least 7 | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) | 1985-01-01 | — | — | US | disclosed |
| US-4362807-A | SUBBLING LAYER ADHERES MASKING LAYER TO SILVER HALIDE EMULSION LAYER | FUJI PHOTO FILM CO., LTD. (JP) | 1982-12-07 | — | — | US | disclosed |
| US-4336316-A | PHOTOSENSITIVE MASK FROM THE THERMAL DECOMPOSITION OF BINDER; SILVER HALIDE EMULSIONS; HEAT RESISTANCE; CONTRAST | FUJI PHOTO FILM CO., LTD. (JP) | 1982-06-22 | — | — | US | disclosed |
| US-4297436-A | ETCHING HYDROPHILIC METAL LAYER TO EXPOSE AN OLEOPHILIC METAL LAYER BELOW | FUJI PHOTO FILM CO., LTD. (JP) | 1981-10-27 | — | — | US | disclosed |
| US-4284713-A | SILVER, SILVER HALIDE OR BINDER IMAGE, MASKING, EXPOSURE, DEVELOPMENT, DECOMPOSITION, ALKALI HALATE OR HALITE, ETCHING | FUJI PHOTO FILM CO., LTD. (JP) | 1981-08-18 | — | — | US | disclosed |
| US-4207105-A | PHOTOGRAPHY | FUJI PHOTO FILM CO., LTD. (JP) | 1980-06-10 | — | — | US | disclosed |
| US-4113486-A | METHOD FOR PRODUCING A PHOTOMASK | FUJI PHOTO FILM CO., LTD. (JP) | 1978-09-12 | — | — | US | disclosed |
| US-4110114-A | SILVER HALIDE EMULSION, ION BOMBARDMENT | FUJI PHOTO FILM CO., LTD. (JP) | 1978-08-29 | — | — | US | disclosed |
| US-4059445-A | SILVER HALIDE EMULSION PHOTOGRAPHY | FUJI PHOTO FILM CO., LTD. (JA) | 1977-11-22 | — | — | US | disclosed |
| US-4056395-A | Method for producing a relief pattern by ion-etching a photographic support | FUJI PHOTO FILM CO., LTD. (JA) | 1977-11-01 | — | — | US | disclosed |
| US-4025345-A | Method of preparing bleached phase hologram and a bleaching solution composition therefor | FUJI PHOTO FILM CO., LTD. (JA) | 1977-05-24 | — | — | US | disclosed |
| US-3966473-A | SILVER HALIDE EMULSION | FUJI PHOTO FILM CO., LTD. (JA) | 1976-06-29 | — | — | US | disclosed |
| US-3960560-A | SILVER HALIDE EMULSION | FUJI PHOTO FILM CO., LTD. (JA) | 1976-06-01 | — | — | US | disclosed |