Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 2/20 | 0.38 |
| ▸ | MAOA | P21397 | 2/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11292349 | 0.84 | HTR6 (0.43) | HTR6MAOAMAOBCYP1A2CYP3A4 | |
| SCHEMBL11292287 | 0.73 | MAOA (0.44) | MAOAMAOBCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL10966476 | 0.67 | MAOA (0.39) | HTR6MAOAMAOBCYP1A2CYP3A4 | |
| SCHEMBL11283989 | 0.61 | MAOA (0.42) | HTR6MAOAMAOBCYP1A2CYP3A4 | |
| SCHEMBL11296073 | 0.61 | MAOA (0.49) | MAOAMAOBCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL15781372 | 0.59 | CYP1A2 (0.62) | MAOACYP1A2CYP3A4CYP2C19MAPT | |
| SCHEMBL26625828 | 0.58 | ALDH1A1 (0.34) | CYP1A2MAPTLMNACYP2D6CYP2C9 | |
| SCHEMBL16471661 | 0.57 | MCL1 (0.39) | CYP3A4TSHRHTTMAPTMCL1 | |
| SCHEMBL11408384 | 0.56 | HSD17B10 (0.47) | MAOACYP1A2CYP3A4CYP2C19MAPK1 | |
| SCHEMBL9026407 | 0.56 | CA2 (0.40) | CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0060640-A1 | 5,6,7-Trinor-4,8-inter-m-phenylene PGI derivatives and pharmaceutical compositions containing them | TORAY INDUSTRIES, INC. (JP) | 1982-09-22 | — | — | EP | disclosed |