Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SNCA | P37840 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL8002981 | 0.96 | HIF1A (0.46) | HIF1ATSHRALDH1A1CYP1A2CYP2D6 | |
| Bromide SCHEMBL8012852 | 0.96 | HIF1A (0.46) | HIF1ATSHRALDH1A1CYP1A2CYP2D6 | |
| Hydrochloric Acid SCHEMBL11657022 | 0.83 | HIF1A (0.43) | HIF1ATSHRALDH1A1CYP1A2CYP2D6 | |
| Hydrochloric Acid SCHEMBL9438410 | 0.80 | LTA4H (0.43) | HIF1ATSHRALDH1A1CYP1A2CYP2D6 | |
| Hydrochloric Acid SCHEMBL9806639 | 0.79 | HIF1A (0.54) | HIF1ATSHRALDH1A1CYP1A2CYP2D6 | |
| Bromide SCHEMBL11659210 | 0.79 | HIF1A (0.43) | HIF1ATSHRALDH1A1CYP1A2CYP2D6 | |
| Hydrochloric Acid SCHEMBL11657635 | 0.79 | LTA4H (0.43) | HIF1ATSHRALDH1A1LTA4HLMNA | |
| Hydrochloric Acid SCHEMBL30084976 | 0.78 | HIF1A (0.41) | HIF1ATSHRALDH1A1CYP1A2CYP2D6 | |
| Hydrochloric Acid SCHEMBL30084961 | 0.78 | HIF1A (0.41) | HIF1ATSHRALDH1A1CYP1A2CYP2D6 | |
| Hydrochloric Acid SCHEMBL11654205 | 0.77 | USP2 (0.43) | TSHRALDH1A1MEN1KMT2ALTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118878430-A | Compound, synthesis method thereof and synthesis method of 5, 6-dihydroxyindole | 谱尼生物医药科技(上海)有限公司 | 2024-11-01 | — | — | CN | claimed |
| US-12415769-B2 | Vinylether compounds and processes for preparing aldehyde compounds and a carboxylate compound therefrom | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2025-09-16 | — | — | US | disclosed |
| CN-118878430-A | Compound, synthesis method thereof and synthesis method of 5, 6-dihydroxyindole | 谱尼生物医药科技(上海)有限公司 | 2024-11-01 | — | — | CN | disclosed |
| EP-4119535-B1 | ACETAL COMPOUNDS, PROCESSES FOR THEIR PREPARATION, AND PROCESSES FOR PREPARING ALDEHYDE COMPOUNDS FROM THE ACETAL COMPOUNDS | SHINETSU CHEMICAL CO (JP) | 2024-02-21 | — | — | EP | disclosed |
| EP-4119537-B1 | VINYLETHER COMPOUNDS, ALDEHYDE COMPOUND, PROCESS FOR PREPARING THE ALDEHYDE COMPOUND AND A CARBOXYLATE COMPOUND THEREFROM | SHINETSU CHEMICAL CO (JP) | 2023-12-13 | — | — | EP | disclosed |
| US-11661390-B2 | Acetal compounds and processes for preparing thereof, and processes for preparing aldehyde compounds from the acetal compounds | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2023-05-30 | — | — | US | disclosed |
| US-20230062627-A1 | ACETAL COMPOUNDS AND PROCESSES FOR PREPARING THEREOF, AND PROCESSES FOR PREPARING ALDEHYDE COMPOUNDS FROM THE ACETAL COMPOUNDS | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2023-03-02 | — | — | US | disclosed |
| US-11584765-B2 | Polycyclic amines as sigma receptor modulators | Ecstasy LLC (US) | 2023-02-21 | — | — | US | disclosed |
| CN-110662541-B | Polycyclic amines as opioid receptor modulators | 王晓冬 | 2023-02-10 | — | — | CN | disclosed |
| US-20230014797-A1 | VINYLETHER COMPOUNDS AND PROCESSES FOR PREPARING ALDEHYDE COMPOUNDS AND A CARBOXYLATE COMPOUND THEREFROM | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2023-01-19 | — | — | US | disclosed |
| US-5693841-A | Cyclohexanone compounds, process for preparing the same, and processes for preparing silacyclohexane-based liquid crystal compounds from the cyclohexanone compounds | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1997-12-02 | — | — | US | disclosed |
| EP-0765880-A1 | Process for preparing sil acyclohexane-based liquid crystal compounds from silacyclohexanone compounds | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1997-04-02 | — | — | EP | disclosed |
| US-5595686-A | Silacyclohexane compounds, a liquid crystal composition comprising the same and a liquid crystal device comprising the composition | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1997-01-21 | — | — | US | disclosed |
| US-5527490-A | Silacyclohexane carbaldehyde compounds and processes for preparing silacyclohexane-based liquid crystal compounds from the carbaldehyde compound | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-06-18 | — | — | US | disclosed |
| US-5519156-A | Cyclohexane carbaldehyde compounds and processes for preparing silacyclohexane-based liquid crystal compounds from the carbaldehyde | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-05-21 | — | — | US | disclosed |
| EP-0699683-A1 | Novel silacyclohexane compounds a liquid crystal composition comprising the same and a liquid crystal device comprising the composition | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-03-06 | — | — | EP | disclosed |
| EP-0692485-A1 | Cyclohexane carbaldehyde compounds and processes for preparing silacyclohexane-based liquid crystal compounds from the carbaldehyde compound | Shin-Etsu Chemical Co., Ltd. (JP) | 1996-01-17 | — | — | EP | disclosed |
| EP-0687678-A1 | Cyclohexanone compounds, process for preparing the same, and processes for preparing silacyclohexane-based liquid crystal compounds from the cyclohexanone compounds | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1995-12-20 | — | — | EP | disclosed |
| EP-0682031-A1 | Silacyclohexane carbaldehyde compounds and processes for preparing silycyclohexane-based liquid crystal compounds from the carbaldehyde compound | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1995-11-15 | — | — | EP | disclosed |
| US-4173463-A | Phosphonium salts as herbicides | SHELL OIL COMPANY (US) | 1979-11-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11584765-B2 | Polycyclic amines as sigma receptor modulators | OPRM1, SIGMAR1, OPRK1 | ACHE 1582/4885HIF1A 1466/4885TSHR 845/4885 |
| US-12415769-B2 | Vinylether compounds and processes for preparing aldehyde compounds and a carboxylate compound therefrom | MMAB, CYP4F2, ALDH16A1 | ACHE 2692/4885HIF1A 1562/4885TSHR 2944/4885 |
| US-20230062627-A1 | ACETAL COMPOUNDS AND PROCESSES FOR PREPARING THEREOF, AND PROCESSES FOR PREPARING ALDEHYDE COMPOUNDS FROM THE ACETAL COMPOUNDS | DHPS, AKR1C4, AKR1C2 | ACHE 1535/4885HIF1A 436/4885TSHR 4210/4885 |
| US-20230014797-A1 | VINYLETHER COMPOUNDS AND PROCESSES FOR PREPARING ALDEHYDE COMPOUNDS AND A CARBOXYLATE COMPOUND THEREFROM | MMAB, CYP4F2, ALDH16A1 | ACHE 2692/4885HIF1A 1562/4885TSHR 2944/4885 |
| US-11661390-B2 | Acetal compounds and processes for preparing thereof, and processes for preparing aldehyde compounds from the acetal compounds | DHPS, AKR1C4, AKR1C2 | ACHE 1535/4885HIF1A 436/4885TSHR 4210/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.