Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | CDC25B | P30305 | 4/20 | 0.43 |
| ▸ | DUSP3 | P51452 | 4/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | DHODH | Q02127 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 5/20 | 0.41 |
| ▸ | MAOB | P27338 | 5/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | ALPL | P05186 | 1/20 | 0.40 |
| ▸ | ALPI | P09923 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1745496 | 0.81 | MAOA (0.58) | ALDH1A1GAAMAPTRAB9APTPN1 | |
| SCHEMBL8188518 | 0.75 | ALDH1A1 (0.56) | ALDH1A1GAAMAPTRAB9ANPC1 | |
| SCHEMBL1108681 | 0.74 | ALDH1A1 (0.56) | ALDH1A1GAAMAPTRAB9APKM | |
| SCHEMBL27834214 | 0.73 | MAOA (0.60) | ALDH1A1MAPTRAB9APTPN1MAOA | |
| Bromide SCHEMBL1744987 | 0.73 | ALDH1A1 (0.54) | ALDH1A1GAAMAPTRAB9APKM | |
| SCHEMBL16217976 | 0.71 | PPARD (0.48) | ALDH1A1GAAMAPTMAOBNPC1 | |
| SCHEMBL96684 | 0.69 | RARA (0.61) | ALDH1A1GAAMAPTDHODHNPC1 | |
| SCHEMBL4268165 | 0.69 | MEN1 (0.59) | MAPTCYP1A2 | |
| SCHEMBL28276133 | 0.68 | DHODH (0.45) | ALDH1A1GAAMAPTDHODHCYP1A2 | |
| SCHEMBL8066329 | 0.68 | ALDH1A1 (0.56) | ALDH1A1MAPTRAB9AMAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1916234-B1 | CYCLOPROPANECARBOXYLIC ACID COMPOUND | TAKEDA PHARMACEUTICAL (JP) | 2014-11-12 | — | — | EP | disclosed |
| US-8153694-B2 | Cyclopropanecarboxylic acid compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-04-10 | — | — | US | disclosed |
| US-20100144806-A1 | Cyclopropanecarboxylic Acid Compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-06-10 | — | — | US | disclosed |
| EP-1916234-A1 | CYCLOPROPANECARBOXYLIC ACID COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2008-04-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100144806-A1 | Cyclopropanecarboxylic Acid Compound | GPR65, GPR34, GPR68 | ALDH1A1 1309/4885GAA 3673/4885MAPT 2525/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.