Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 12/20 | 0.58 |
| ▸ | MAOB | P27338 | 12/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.51 |
| ▸ | XIAP | P98170 | 1/20 | 0.50 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27834214 | 0.91 | MAOA (0.60) | MAOAMAOBALDH1A1HSD17B10CYP1A2 | |
| SCHEMBL8066329 | 0.85 | ALDH1A1 (0.56) | MAOAMAOBALDH1A1HSD17B10CYP1A2 | |
| Bromide SCHEMBL11366637 | 0.84 | ALDH1A1 (0.55) | MAOAMAOBALDH1A1HSD17B10CYP1A2 | |
| Hydrochloric Acid SCHEMBL9255930 | 0.82 | MAOA (0.50) | MAOAMAOBALDH1A1HSD17B10CYP1A2 | |
| SCHEMBL27642190 | 0.81 | ALOX5 (0.51) | MAOAMAOBALDH1A1HSD17B10CYP1A2 | |
| SCHEMBL1099004 | 0.81 | ALDH1A1 (0.50) | MAOAMAOBALDH1A1HSD17B10CYP1A2 | |
| SCHEMBL5360082 | 0.80 | ALOX5 (0.56) | MAOAMAOBALDH1A1HSD17B10CYP1A2 | |
| SCHEMBL1745085 | 0.78 | MAOA (0.62) | MAOAMAOBALDH1A1HSD17B10CYP1A2 | |
| SCHEMBL25327043 | 0.77 | MAOA (0.60) | MAOAMAOBALDH1A1HSD17B10CYP1A2 | |
| SCHEMBL27852308 | 0.76 | PTGS2 (0.59) | ALDH1A1MAPTMEN1KMT2AXIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1559422-B1 | RECEPTOR FUNCTION CONTROLLING AGENT | TAKEDA PHARMACEUTICAL (JP) | 2014-04-30 | — | — | EP | disclosed |
| EP-2385032-A1 | GPR40 Receptor function regulator | Takeda Pharmaceutical Company Limited (JP) | 2011-11-09 | — | — | EP | disclosed |
| US-7960369-B2 | Receptor function regulator | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2011-06-14 | — | — | US | disclosed |
| US-20090012093-A1 | Receptor Function Regulator | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-01-08 | — | — | US | disclosed |
| EP-1559422-A1 | RECEPTOR FUNCTION CONTROLLING AGENT | Takeda Pharmaceutical Company Limited (JP) | 2005-08-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090012093-A1 | Receptor Function Regulator | GPR119, GIPR, INSR | MAOA 4245/4885MAOB 4303/4885ALDH1A1 4258/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.