Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1D | Q01668 | 1/20 | 0.38 |
| ▸ | CSNK1D | P48730 | 4/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MC4R | P32245 | 2/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | DHFR | P00374 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12179711 | 0.91 | CACNA1D (0.38) | CACNA1DCSNK1DPTGS1KDM4EMC4R | |
| SCHEMBL1098570 | 0.86 | ALDH1A1 (0.43) | KDM4EMEN1KMT2A | |
| SCHEMBL1100175 | 0.85 | KDM4E (0.35) | KDM4EMEN1KMT2A | |
| SCHEMBL1100991 | 0.85 | NPC1 (0.44) | KDM4EPKMMEN1KMT2A | |
| SCHEMBL9100960 | 0.84 | CACNA1D (0.39) | CACNA1DCSNK1DPTGS1KDM4EPKM | |
| SCHEMBL1099556 | 0.83 | NPC1 (0.42) | KDM4EMEN1KMT2A | |
| SCHEMBL1098519 | 0.83 | RAB9A (0.46) | KDM4E | |
| SCHEMBL1100125 | 0.82 | NPC1 (0.39) | KDM4EMEN1KMT2A | |
| SCHEMBL825192 | 0.82 | CSNK1D (0.36) | CACNA1DCSNK1DPTGS1MC4RMEN1 | |
| SCHEMBL20961133 | 0.82 | MC4R (0.36) | CACNA1DCSNK1DPTGS1MC4RMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2346840-B1 | UV/VISIBLE LIGHT ABSORBERS FOR OPHTHALMIC LENS MATERIALS | NOVARTIS AG (CH) | 2013-12-25 | — | — | EP | disclosed |
| US-8262948-B2 | Intraocular lenses with combinations of UV absorbers and blue light chromophores | NOVARTIS AG (CH) | 2012-09-11 | — | — | US | disclosed |
| US-8232326-B2 | UV/visible light absorbers for ophthalmic lens materials | NOVARTIS AG (CH) | 2012-07-31 | — | — | US | disclosed |
| US-8232326-B2 | UV/visible light absorbers for ophthalmic lens materials | NOVARTIS AG (CH) | 2012-07-31 | — | — | US | disclosed |
| US-20120142877-A1 | UV/VISIBLE LIGHT ABSORBERS FOR OPHTHALMIC LENS MATERIALS | NOVARTIS AG (CH) | 2012-06-07 | — | — | US | disclosed |
| US-20120142877-A1 | UV/VISIBLE LIGHT ABSORBERS FOR OPHTHALMIC LENS MATERIALS | NOVARTIS AG (CH) | 2012-06-07 | — | — | US | disclosed |
| US-8153703-B2 | UV/visible light absorbers for ophthalmic lens materials | NOVARTIS AG (CH) | 2012-04-10 | — | — | US | disclosed |
| US-8153703-B2 | UV/visible light absorbers for ophthalmic lens materials | NOVARTIS AG (CH) | 2012-04-10 | — | — | US | disclosed |
| US-8153703-B2 | UV/visible light absorbers for ophthalmic lens materials | NOVARTIS AG (CH) | 2012-04-10 | — | — | US | disclosed |
| US-20110266505-A1 | INTRAOCULAR LENSES WITH COMBINATIONS OF UV ABSORBERS AND BLUE LIGHT CHROMOPHORES | ALCON INC. (CH) | 2011-11-03 | — | — | US | disclosed |
| EP-2346840-A1 | UV/VISIBLE LIGHT ABSORBERS FOR OPHTHALMIC LENS MATERIALS | Alcon, Inc. (CH) | 2011-07-27 | — | — | EP | disclosed |
| WO-2010053917-A1 | UV/VISIBLE LIGHT ABSORBERS FOR OPHTHALMIC LENS MATERIALS | ALCON, INC. (CH) | 2010-05-14 | — | — | WO | disclosed |
| US-20100113641-A1 | UV/VISIBLE LIGHT ABSORBERS FOR OPHTHALMIC LENS MATERIALS | ALCON, INC. (CH) | 2010-05-06 | — | — | US | disclosed |
| US-20100113641-A1 | UV/VISIBLE LIGHT ABSORBERS FOR OPHTHALMIC LENS MATERIALS | ALCON, INC. (CH) | 2010-05-06 | — | — | US | disclosed |
| US-20100113641-A1 | UV/VISIBLE LIGHT ABSORBERS FOR OPHTHALMIC LENS MATERIALS | ALCON, INC. (CH) | 2010-05-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100113641-A1 | UV/VISIBLE LIGHT ABSORBERS FOR OPHTHALMIC LENS MATERIALS | UACA, CRYZ, CRYAA | CACNA1D 2651/4885CSNK1D 4202/4885PTGS1 1296/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.