Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.36 |
| ▸ | PDE5A | O76074 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | GSK3A | P49840 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28126381 | 0.75 | MAPT (0.44) | KMT2AALDH1A1MAPTCYP3A4NPC1 | |
| SCHEMBL8435546 | 0.74 | ALOX15 (0.55) | KMT2AALDH1A1ALOX15KDM4EL3MBTL1 | |
| SCHEMBL3832725 | 0.74 | CYP19A1 (0.47) | KMT2AALDH1A1KDM4EL3MBTL1NPSR1 | |
| SCHEMBL28169221 | 0.73 | FABP5 (0.49) | KMT2AALDH1A1MAPTNPSR1SMN1; SMN2 | |
| SCHEMBL28006254 | 0.72 | KDM4E (0.55) | KMT2AALDH1A1KDM4EPDE5ANPSR1 | |
| SCHEMBL29852338 | 0.72 | P2RX7 (0.44) | ALOX15L3MBTL1ELANESMN1; SMN2 | |
| SCHEMBL9487319 | 0.71 | TDP1 (0.52) | KMT2AALDH1A1MAPTELANETDP1 | |
| SCHEMBL27690138 | 0.71 | LMNA (0.45) | KMT2AALOX15KDM4EL3MBTL1CYP3A4 | |
| SCHEMBL9858688 | 0.71 | HCAR3 (0.47) | KMT2AALDH1A1KDM4EHCAR2NPC1 | |
| SCHEMBL1533873 | 0.71 | CYP3A4 (0.43) | KMT2AALDH1A1ALOX15KDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4536208-A | Certain naphthyridine diether compounds and their herbicidal use | THE DOW CHEMICAL COMPANY (US) | 1985-08-20 | — | — | US | disclosed |
| US-4533381-A | Naphthyridinyloxy(or thio)phenoxy propanoic acids, derivatives thereof and methods of herbicidal use | THE DOW CHEMICAL COMPANY (US) | 1985-08-06 | — | — | US | disclosed |
| US-4472193-A | Naphthyridinyloxy(or thio)phenoxy propanoic acids, derivatives thereof and methods of herbicidal use | THE DOW CHEMICAL COMPANY (US) | 1984-09-18 | — | — | US | disclosed |