Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 14/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 14/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 13/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 12/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 7/20 | 0.48 |
| ▸ | SCD | O00767 | 1/20 | 0.46 |
| ▸ | CFB | P00751 | 3/20 | 0.45 |
| ▸ | ATR | Q13535 | 1/20 | 0.45 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.45 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11018077 | 0.93 | CYP2C9 (0.54) | CYP3A4CYP2C9CYP1A2CYP2C19CYP2D6 | |
| SCHEMBL10763275 | 0.92 | MAPK10 (0.42) | CYP3A4CYP2C9CYP1A2CYP2C19CYP2D6 | |
| SCHEMBL11021898 | 0.89 | ATR (0.53) | SCDCFBATRPKN1PKN2 | |
| SCHEMBL11020318 | 0.88 | CA12 (0.54) | SCDCFBATRPKN1PKN2 | |
| SCHEMBL11016115 | 0.87 | CFB (0.47) | CFBATRPKN1PKN2 | |
| SCHEMBL11018866 | 0.87 | MAPT (0.44) | CFBATRPKN1PKN2 | |
| SCHEMBL11021561 | 0.86 | L3MBTL1 (0.47) | CYP3A4CYP2C9CYP2D6CFBATR | |
| SCHEMBL11017639 | 0.86 | MAPT (0.49) | CYP3A4CYP2C9CYP2D6CFBATR | |
| SCHEMBL11018071 | 0.85 | CYP2C9 (0.47) | CYP3A4CYP2C9CYP1A2CYP2C19CYP2D6 | |
| SCHEMBL11022217 | 0.82 | ATR (0.53) | SCDATRPKN1PKN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0148431-A1 | Benzimidazoles, their preparation, and medicaments containing these compounds | Dr. Karl Thomae GmbH (DE) | 1985-07-17 | — | — | EP | disclosed |