Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 5/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | CFB | P00751 | 4/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | ATR | Q13535 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11017633 | 0.93 | ALDH1A1 (0.44) | MAPTALDH1A1PKMUSP2POLB | |
| SCHEMBL11018077 | 0.88 | CYP2C9 (0.54) | CFBATRCYP3A4CYP2D6CYP2C9 | |
| SCHEMBL11016115 | 0.88 | CFB (0.47) | MAPTALDH1A1LMNAHTTMEN1 | |
| SCHEMBL11018186 | 0.86 | CYP3A4 (0.48) | CFBATRCYP3A4CYP2D6CYP2C9 | |
| SCHEMBL11021898 | 0.84 | ATR (0.53) | CFBATRPKN1PKN2 | |
| SCHEMBL11020318 | 0.83 | CA12 (0.54) | ALDH1A1HPGDCFBATRPKN1 | |
| SCHEMBL11021561 | 0.83 | L3MBTL1 (0.47) | MAPTALDH1A1LMNAHTTMEN1 | |
| SCHEMBL11018866 | 0.82 | MAPT (0.44) | MAPTALDH1A1LMNAHTTMEN1 | |
| SCHEMBL11021240 | 0.81 | MAPT (0.46) | MAPTALDH1A1PKMUSP2POLB | |
| SCHEMBL11018071 | 0.80 | CYP2C9 (0.47) | ATRCYP3A4CYP2D6CYP2C9SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0148431-A1 | Benzimidazoles, their preparation, and medicaments containing these compounds | Dr. Karl Thomae GmbH (DE) | 1985-07-17 | — | — | EP | disclosed |