Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 6/20 | 0.54 |
| ▸ | CA9 | Q16790 | 6/20 | 0.54 |
| ▸ | CA12 | O43570 | 5/20 | 0.54 |
| ▸ | CA1 | P00915 | 5/20 | 0.54 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ATR | Q13535 | 1/20 | 0.39 |
| ▸ | AMY1A | P0DUB6 | 2/20 | 0.39 |
| ▸ | PDE5A | O76074 | 1/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 5/20 | 0.38 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11020318 | 0.92 | CA12 (0.54) | CA2CA9CA12CA1KDM4E | |
| SCHEMBL11021893 | 0.90 | ATR (0.44) | CA2CA9CA12CA1MAPK10 | |
| SCHEMBL11021081 | 0.89 | CA12 (0.43) | CA2CA9CA12CA1MAPK10 | |
| SCHEMBL10763275 | 0.88 | MAPK10 (0.42) | CA2CA9CA12CA1MAPK10 | |
| SCHEMBL11018857 | 0.88 | MAPT (0.44) | CA2CA9CA12CA1MAPK10 | |
| SCHEMBL11016112 | 0.88 | SCN9A (0.42) | CA2CA9CA12CA1MAPK10 | |
| SCHEMBL11018071 | 0.86 | CYP2C9 (0.47) | CA2CA9CA12CA1MAPK10 | |
| SCHEMBL10765238 | 0.84 | CDK4 (0.45) | CA2CA9CA12CA1KDM4E | |
| SCHEMBL11021552 | 0.83 | L3MBTL1 (0.47) | CA2CA9CA12CA1MAPK10 | |
| SCHEMBL11017633 | 0.83 | ALDH1A1 (0.44) | CA2CA9CA12CA1MAPK10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0148431-A1 | Benzimidazoles, their preparation, and medicaments containing these compounds | Dr. Karl Thomae GmbH (DE) | 1985-07-17 | — | — | EP | disclosed |