Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | LSS | P48449 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 5/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11235692 | 0.74 | KDM4E (0.43) | POLBKDM4EPKMLMNAPDK2 | |
| SCHEMBL20274372 | 0.72 | ZDHHC20 (0.47) | — | |
| SCHEMBL20274387 | 0.71 | ALDH1A1 (0.44) | LSSKDM4ELMNAMAPT | |
| SCHEMBL8033183 | 0.70 | ALDH1A1 (0.47) | MAPT | |
| SCHEMBL17445904 | 0.70 | PDK2 (0.46) | POLBKDM4EPKMLMNAPDK2 | |
| SCHEMBL11091963 | 0.70 | GAA (0.44) | KDM4EPKMLMNA | |
| SCHEMBL7322958 | 0.67 | CYP1A2 (0.45) | POLBKDM4EPKMLMNAPDK2 | |
| SCHEMBL9067643 | 0.67 | HPGD (0.52) | LSS | |
| SCHEMBL11090567 | 0.66 | KDM4E (0.71) | KDM4EPKMLMNAPDK2SLC6A2 | |
| SCHEMBL29161778 | 0.66 | PDK2 (0.39) | POLBKDM4EPKMLMNAPDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4508735-A | ALSO ANESTHETIC | ELI LILLY AND COMPANY (US) | 1985-04-02 | — | — | US | disclosed |