Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 3/20 | 0.38 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.38 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.38 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | AURKA | O14965 | 1/20 | 0.34 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10746448 | 0.93 | TXNRD1 (0.43) | METAP2TXNRD1TXNRD3TXNRD2MAPT | |
| SCHEMBL10743453 | 0.89 | METAP2 (0.34) | METAP2MAPTKMT2AKDM4EALDH1A1 | |
| SCHEMBL10748075 | 0.82 | MAPT (0.40) | METAP2MAPTNPC1RAB9AKMT2A | |
| SCHEMBL10501980 | 0.79 | METAP2 (0.41) | METAP2TXNRD1TXNRD3TXNRD2MAPT | |
| SCHEMBL10747300 | 0.78 | NR4A2 (0.33) | METAP2KMT2AALDH1A1 | |
| SCHEMBL10745708 | 0.77 | TXNRD1 (0.56) | METAP2TXNRD1TXNRD3TXNRD2MAPT | |
| SCHEMBL10501631 | 0.75 | MAT2A (0.38) | METAP2MAPTKDM4EALDH1A1HPGD | |
| SCHEMBL10503543 | 0.74 | METAP2 (0.50) | METAP2TXNRD1TXNRD3TXNRD2MAPT | |
| SCHEMBL10501833 | 0.73 | NPC1 (0.43) | METAP2TXNRD1TXNRD3TXNRD2MAPT | |
| SCHEMBL10745932 | 0.72 | METAP2 (0.45) | METAP2MAPTKMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0154851-A1 | Benzisoselenazolethiones,process for their preparation and pharmaceutical products containing these compounds | A. Nattermann & Cie. GmbH (DE) | 1985-09-18 | — | — | EP | disclosed |