Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.34 |
| ▸ | KMO | O15229 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | PLAU | P00749 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.30 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11026970 | 0.83 | TDP1 (0.46) | TDP1KMO | |
| SCHEMBL2599666 | 0.81 | L3MBTL1 (0.45) | TDP1MAPTATML3MBTL1LMNA | |
| Picloram SCHEMBL13299 | 0.77 | TDP1 (1.00) | TDP1MAPTATML3MBTL1LMNA | |
| Picloram SCHEMBL29388079 | 0.77 | TDP1 (1.00) | TDP1MAPTATML3MBTL1LMNA | |
| Picloram SCHEMBL8467014 | 0.77 | TDP1 (1.00) | TDP1MAPTATML3MBTL1LMNA | |
| Picloram SCHEMBL15437675 | 0.76 | TDP1 (0.96) | TDP1MAPTATML3MBTL1LMNA | |
| Picloram SCHEMBL5086801 | 0.76 | TDP1 (0.96) | TDP1MAPTATML3MBTL1LMNA | |
| Picloram SCHEMBL7112378 | 0.76 | TDP1 (0.96) | TDP1MAPTATML3MBTL1LMNA | |
| Picloram SCHEMBL29705200 | 0.76 | TDP1 (0.96) | TDP1MAPTATML3MBTL1LMNA | |
| Picloram SCHEMBL28547325 | 0.76 | TDP1 (0.96) | TDP1MAPTATML3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8835409-B2 | 3-alkenyl-6-halo-4-aminopicolinates and their use as herbicides | DOW AGROSCIENCES, LLC. (US) | 2014-09-16 | — | — | US | disclosed |
| US-8835409-B2 | 3-alkenyl-6-halo-4-aminopicolinates and their use as herbicides | DOW AGROSCIENCES, LLC. (US) | 2014-09-16 | — | — | US | disclosed |
| US-8835409-B2 | 3-alkenyl-6-halo-4-aminopicolinates and their use as herbicides | DOW AGROSCIENCES, LLC. (US) | 2014-09-16 | — | — | US | disclosed |
| US-20130065757-A1 | CHEMICAL COMPOUNDS | SYNGENTA LIMITED (GB) | 2013-03-14 | — | — | US | disclosed |
| US-20130065757-A1 | CHEMICAL COMPOUNDS | SYNGENTA LIMITED (GB) | 2013-03-14 | — | — | US | disclosed |
| US-20130065757-A1 | CHEMICAL COMPOUNDS | SYNGENTA LIMITED (GB) | 2013-03-14 | — | — | US | disclosed |
| US-20120190548-A1 | 3-ALKENYL-6-HALO-4-AMINOPICOLINATES AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2012-07-26 | — | — | US | disclosed |
| US-20120190548-A1 | 3-ALKENYL-6-HALO-4-AMINOPICOLINATES AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2012-07-26 | — | — | US | disclosed |
| US-20120190548-A1 | 3-ALKENYL-6-HALO-4-AMINOPICOLINATES AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2012-07-26 | — | — | US | disclosed |
| WO-2011144891-A1 | CHEMICAL COMPOUNDS | SYNGENTA LIMITED (GB) | 2011-11-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130065757-A1 | CHEMICAL COMPOUNDS | HPD, PPOX, PIN1 | TDP1 2573/4885MAPT 2450/4885ATM 4359/4885 |
| US-20120190548-A1 | 3-ALKENYL-6-HALO-4-AMINOPICOLINATES AND THEIR USE AS HERBICIDES | ATL3, AAAS, HDHD5 | TDP1 3735/4885MAPT 961/4885ATM 3960/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.