SCHEMBL11027477

SCHEMBL11027477

COC1CCC(N)(C#N)CC1

nearest known ligand 0.36

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 3/20 0.36
SLC6A4 P31645 3/20 0.33
SLC6A3 Q01959 3/20 0.33
APP P05067 1/20 0.32
BACE1 P56817 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL11030927 0.98 DPP4 (0.35) DPP4SLC6A4SLC6A3APPBACE1
Formic Acid SCHEMBL11895985 0.89 DPP4 (0.31) DPP4
Formic Acid SCHEMBL11895987 0.89 DPP4 (0.31) DPP4
SCHEMBL26703732 0.76 SLC6A4 (0.33) DPP4SLC6A4SLC6A3BACE1
SCHEMBL1809829 0.75
SCHEMBL1809831 0.75
SCHEMBL1809828 0.75
SCHEMBL24643163 0.74 DPP4 (0.37) DPP4SLC6A4SLC6A3
SCHEMBL21242271 0.72
SCHEMBL12852762 0.72 ALDH1A1 (0.44) DPP4SLC6A4SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12612359-B2 Cis-para-substituted cyclohexylaminonitrile salt, preparation method therefor and use thereof, and method for preparing pesticide using same Lansheng Biotechnology Group Co., Ltd. (CN) 2026-04-28 US disclosed
WO-2025243298-A1 NOVEL SUBSTITUTED AMINOCYCLOHEXANECARBONITRILES ADAMA MAKHTESHIM LTD. (IL) 2025-11-27 WO disclosed
WO-2025243298-A1 NOVEL SUBSTITUTED AMINOCYCLOHEXANECARBONITRILES ADAMA MAKHTESHIM LTD. (IL) 2025-11-27 WO disclosed
EP-4234533-A1 CIS-PARA-SUBSTITUTED CYCLOHEXYLAMINONITRILE SALT, PREPARATION METHOD THEREFOR AND USE THEREOF, AND METHOD FOR PREPARING PESTICIDE USING SAME Hebei Lansheng Biotech Co., Ltd (CN) 2023-08-30 EP disclosed
US-20230257341-A1 CIS-PARA-SUBSTITUTED CYCLOHEXYLAMINONITRILE SALT, PREPARATION METHOD THEREFOR AND USE THEREOF, AND METHOD FOR PREPARING PESTICIDE USING SAME HEBEI LANSHENG BIOTECH CO., LTD (CN) 2023-08-17 US disclosed
CN-115427393-B Cis-para-substituted cyclohexylamino nitrile salts, method for the production and use thereof, and method for producing pesticides using same 河北兰升生物科技有限公司 2023-05-26 CN disclosed
CN-115427393-A Cis-para-substituted cyclohexylamino nitrile salts, process for their preparation and their use, and process for preparing pesticides using them 河北兰升生物科技有限公司 2022-12-02 CN disclosed
WO-2022083494-A1 CIS-PARA-SUBSTITUTED CYCLOHEXYLAMINONITRILE SALT, PREPARATION METHOD THEREFOR AND USE THEREOF, AND METHOD FOR PREPARING PESTICIDE USING SAME 河北兰升生物科技有限公司 2022-04-28 WO disclosed
CN-106905215-B Process for preparing 1-H-pyrrolidine-2, 4-dione derivatives 拜耳知识产权有限责任公司 2021-10-01 CN disclosed
EP-3858835-A1 PYRIMIDINE-BASED ANTIPROLIFERATIVE AGENTS G1 Therapeutics, Inc. (US) 2021-08-04 EP disclosed
US-20210047328-A1 PYRIMIDINE-BASED ANTIPROLIFERATIVE AGENTS G1 THERAPEUTICS, INC. (US) 2021-02-18 US disclosed
US-20210047328-A1 PYRIMIDINE-BASED ANTIPROLIFERATIVE AGENTS G1 THERAPEUTICS, INC. (US) 2021-02-18 US disclosed
US-10829490-B2 Substituted dihydropyrazino[1 ′,2′:1,5]pyrrolo[2,3-d]pyrimidine-based antiproliferative agents GI Therapeutics, Inc. (US) 2020-11-10 US disclosed
US-10829490-B2 Substituted dihydropyrazino[1 ′,2′:1,5]pyrrolo[2,3-d]pyrimidine-based antiproliferative agents GI Therapeutics, Inc. (US) 2020-11-10 US disclosed
US-20190135811-A1 PYRIMIDINE-BASED ANTIPROLIFERATIVE AGENTS G1 THERAPEUTICS, INC. (US) 2019-05-09 US disclosed
US-20190135811-A1 PYRIMIDINE-BASED ANTIPROLIFERATIVE AGENTS G1 THERAPEUTICS, INC. (US) 2019-05-09 US disclosed
US-8859782-B2 Process for the preparation of 1-H-pyrrolidine-2,4-dione derivatives BAYER CROPSCIENCE AG (DE) 2014-10-14 US disclosed
US-8680316-B2 Process for the preparation of cis-1-ammonium-4-alkoxycyclohexanecarbonitrile salts BAYER CROPSCIENCE AG (DE) 2014-03-25 US disclosed
US-20120197035-A1 Process for the Preparation of cis-1-ammonium-4-alkoxycyclohexanecarbonitrile Salts BAYER CROPSCIENCE AG (DE) 2012-08-02 US disclosed
US-20120190865-A1 Process for the Preparation of 1-H-pyrrolidine-2,4-dione Derivatives BAYER CROPSCIENCE AG (DE) 2012-07-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190135811-A1 PYRIMIDINE-BASED ANTIPROLIFERATIVE AGENTS TYMP, TYMS, DPYD DPP4 3279/4885SLC6A4 3172/4885SLC6A3 3566/4885
US-20210047328-A1 PYRIMIDINE-BASED ANTIPROLIFERATIVE AGENTS TYMP, TYMS, DPYD DPP4 3279/4885SLC6A4 3172/4885SLC6A3 3566/4885
US-10829490-B2 Substituted dihydropyrazino[1 ′,2′:1,5]pyrrolo[2,3-d]pyrimidine-based antiproliferative agents MKI67, DPYD, PCNA DPP4 1556/4885SLC6A4 3075/4885SLC6A3 2915/4885
US-20230257341-A1 CIS-PARA-SUBSTITUTED CYCLOHEXYLAMINONITRILE SALT, PREPARATION METHOD THEREFOR AND USE THEREOF, AND METHOD FOR PREPARING PESTICIDE USING SAME CYP4F11, CYP4A11, NOTUM DPP4 561/4885SLC6A4 409/4885SLC6A3 647/4885
US-12612359-B2 Cis-para-substituted cyclohexylaminonitrile salt, preparation method therefor and use thereof, and method for preparing pesticide using same SLC6A11, CA2, CYP4F11 DPP4 1403/4885SLC6A4 406/4885SLC6A3 1050/4885
US-20120190865-A1 Process for the Preparation of 1-H-pyrrolidine-2,4-dione Derivatives DHPS, HPD, DOHH DPP4 912/4885SLC6A4 3828/4885SLC6A3 3095/4885
US-20120197035-A1 Process for the Preparation of cis-1-ammonium-4-alkoxycyclohexanecarbonitrile Salts CIAPIN1, CPS1, ALKBH1 DPP4 1419/4885SLC6A4 1161/4885SLC6A3 2445/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.