Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 2/20 | 0.34 |
| ▸ | GRM4 | Q14833 | 4/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.33 |
| ▸ | GRM3 | Q14832 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | GRM8 | O00222 | 1/20 | 0.33 |
| ▸ | GRM6 | O15303 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.33 |
| ▸ | PLCB1 | Q9NQ66 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SOD1 | P00441 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14689539 | 1.00 | EPHX2 (0.35) | EPHX2NPSR1DPP4GRM4GRM2 | |
| SCHEMBL14689536 | 1.00 | EPHX2 (0.35) | EPHX2NPSR1DPP4GRM4GRM2 | |
| Hydrochloric Acid SCHEMBL1943385 | 0.98 | EPHX2 (0.34) | EPHX2NPSR1DPP4GRM4GRM2 | |
| Hydrochloric Acid SCHEMBL1943386 | 0.98 | EPHX2 (0.34) | EPHX2NPSR1DPP4GRM4GRM2 | |
| Hydrochloric Acid SCHEMBL1321280 | 0.98 | EPHX2 (0.34) | EPHX2NPSR1DPP4GRM4GRM2 | |
| SCHEMBL28745251 | 0.82 | DPP4 (0.34) | EPHX2DPP4CYP1A2ALOX15SLC6A4 | |
| SCHEMBL18736369 | 0.82 | MMP1 (0.34) | NPSR1MAPTMMP1 | |
| SCHEMBL24511780 | 0.82 | NPSR1 (0.35) | NPSR1GRM4GRM2GRM3LMNA | |
| SCHEMBL1808341 | 0.82 | NPSR1 (0.35) | NPSR1GRM4GRM2GRM3LMNA | |
| SCHEMBL19696482 | 0.82 | GRM4 (0.47) | DPP4GRM4GRM2GRM3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023274869-A1 | 3-(4-ALKENYL-PHENYL)-3-PYRROLINO-2-ONES AND THEIR USE AS HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2023-01-05 | — | — | WO | disclosed |
| CN-106905215-B | Process for preparing 1-H-pyrrolidine-2, 4-dione derivatives | 拜耳知识产权有限责任公司 | 2021-10-01 | — | — | CN | disclosed |
| WO-2019228788-A1 | 2-BROMO-6-ALKOXYPHENYL-SUBSTITUTED PYRROLIN-2-ONES AND THEIR USE AS HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2019-12-05 | — | — | WO | disclosed |
| US-9272997-B2 | Process for the preparation of 1-H-pyrrolidine-2,4-dione derivatives | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-03-01 | — | — | US | disclosed |
| US-20140371468-A1 | Process for the Preparation of 1-H-pyrrolidine-2,4-dione Derivatives | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2014-12-18 | — | — | US | disclosed |
| US-8859782-B2 | Process for the preparation of 1-H-pyrrolidine-2,4-dione derivatives | BAYER CROPSCIENCE AG (DE) | 2014-10-14 | — | — | US | disclosed |
| WO-2014160649-A1 | HYDROXAMIC ACID DERIVATIVES AS LPXC INHIBITORS FOR THE TREATMENT OF BACTERIAL INFECTIONS | NOVARTIS AG (CH) | 2014-10-02 | — | — | WO | disclosed |
| US-20140038822-A1 | USE OF SUBSTITUTED SPIROCYCLIC SULFONAMIDOCARBOXYLIC ACIDS, CARBOXYLIC ESTERS THEREOF, CARBOXAMIDES THEREOF AND CARBONITRILES THEREOF OR SALTS THEREOF FOR ENHANCEMENT OF STRESS TOLERANCE IN PLANTS | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-02-06 | — | — | US | disclosed |
| CN-103476254-A | Use of substituted spirocyclic sulfonamidocarboxylic acids, carboxylic esters thereof, carboxamides thereof and carbonitriles thereof or salts thereof for enhancement of stress tolerance in plants | BAYER CROPSCIENCE AG | 2013-12-25 | — | — | CN | disclosed |
| EP-2658376-A1 | USE OF SUBSTITUTED SPIROCYCLIC SULFONAMIDOCARBOXYLIC ACIDS, CARBOXYLIC ESTERS THEREOF, CARBOXAMIDES THEREOF AND CARBONITRILES THEREOF OR SALTS THEREOF FOR ENHANCEMENT OF STRESS TOLERANCE IN PLANTS | Bayer Intellectual Property GmbH (DE) | 2013-11-06 | — | — | EP | disclosed |
| US-7803967-B2 | 4-alkoxy-cyclohexane-1-amino-carboxylic esters and processes for their preparation | BAYER CROPSCIENCE AG (DE) | 2010-09-28 | — | — | US | disclosed |
| US-7803967-B2 | 4-alkoxy-cyclohexane-1-amino-carboxylic esters and processes for their preparation | BAYER CROPSCIENCE AG (DE) | 2010-09-28 | — | — | US | disclosed |
| US-20090156402-A1 | 4-ALKOXY-CYCLOHEXANE-1-AMINO-CARBOXYLIC ESTERS AND PROCESSES FOR THEIR PREPARATION | BAYER CROPSCIENCE AG (DE) | 2009-06-18 | — | — | US | disclosed |
| US-20090156402-A1 | 4-ALKOXY-CYCLOHEXANE-1-AMINO-CARBOXYLIC ESTERS AND PROCESSES FOR THEIR PREPARATION | BAYER CROPSCIENCE AG (DE) | 2009-06-18 | — | — | US | disclosed |
| US-7511153-B2 | 4-alkoxy cyclohexane-1 amino carboxylic acid esters and method for the production thereof | BAYER CROPSCIENCE AG (DE) | 2009-03-31 | — | — | US | disclosed |
| US-7511153-B2 | 4-alkoxy cyclohexane-1 amino carboxylic acid esters and method for the production thereof | BAYER CROPSCIENCE AG (DE) | 2009-03-31 | — | — | US | disclosed |
| EP-1309562-B1 | 4-ALKOXY CYCLOHEXANE-1 AMINO CARBOXYLIC ACID ESTERS AND METHOD FOR THE PRODUCTION THEREOF | BAYER CROPSCIENCE AG (DE) | 2008-05-07 | — | — | EP | disclosed |
| US-20070043219-A1 | 4-Alkoxy cyclohexane-1 amino carboxylic acid esters and method for the production thereof | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2007-02-22 | — | — | US | disclosed |
| US-20070043219-A1 | 4-Alkoxy cyclohexane-1 amino carboxylic acid esters and method for the production thereof | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2007-02-22 | — | — | US | disclosed |
| CN-1087904-A | Carboxylic acid derivative, the pharmaceutical composition that contains these compounds with and preparation method thereof | KRAL THOMAE GMBH (DE) | 1994-06-15 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070043219-A1 | 4-Alkoxy cyclohexane-1 amino carboxylic acid esters and method for the production thereof | ALDH7A1, DDC, ABAT | EPHX2 268/4885NPSR1 1380/4885DPP4 162/4885 |
| US-20090156402-A1 | 4-ALKOXY-CYCLOHEXANE-1-AMINO-CARBOXYLIC ESTERS AND PROCESSES FOR THEIR PREPARATION | DDT, CYP4B1, ALDH7A1 | EPHX2 177/4885NPSR1 1774/4885DPP4 77/4885 |
| US-20140038822-A1 | USE OF SUBSTITUTED SPIROCYCLIC SULFONAMIDOCARBOXYLIC ACIDS, CARBOXYLIC ESTERS THEREOF, CARBOXAMIDES THEREOF AND CARBONITRILES THEREOF OR SALTS THEREOF FOR ENHANCEMENT OF STRESS TOLERANCE IN PLANTS | STS, SCLY, TST | EPHX2 1154/4885NPSR1 1683/4885DPP4 3202/4885 |
| US-20140371468-A1 | Process for the Preparation of 1-H-pyrrolidine-2,4-dione Derivatives | DHPS, HPD, DOHH | EPHX2 1885/4885NPSR1 1380/4885DPP4 912/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.