Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.36 |
| ▸ | MGAM | O43451 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SI | P14410 | 1/20 | 0.35 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 4/20 | 0.34 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.32 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.31 |
| ▸ | ASGR1 | P07306 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14924286 | 1.00 | ALDH1A1 (0.43) | ALDH1A1CA2LMNASLC15A2MGAM | |
| SCHEMBL12081795 | 1.00 | ALDH1A1 (0.43) | ALDH1A1CA2LMNASLC15A2MGAM | |
| SCHEMBL15580618 | 1.00 | ALDH1A1 (0.43) | ALDH1A1CA2LMNASLC15A2MGAM | |
| SCHEMBL14924285 | 1.00 | ALDH1A1 (0.43) | ALDH1A1CA2LMNASLC15A2MGAM | |
| SCHEMBL14134546 | 1.00 | ALDH1A1 (0.43) | ALDH1A1CA2LMNASLC15A2MGAM | |
| SCHEMBL16256864 | 1.00 | ALDH1A1 (0.43) | ALDH1A1CA2LMNASLC15A2MGAM | |
| SCHEMBL14134613 | 1.00 | ALDH1A1 (0.43) | ALDH1A1CA2LMNASLC15A2MGAM | |
| SCHEMBL10086608 | 0.89 | ALDH1A1 (0.53) | ALDH1A1LMNASLC15A2MGAMGAA | |
| SCHEMBL18769029 | 0.89 | ALDH1A1 (0.53) | ALDH1A1LMNASLC15A2MGAMGAA | |
| SCHEMBL22198371 | 0.89 | ALDH1A1 (0.53) | ALDH1A1LMNASLC15A2MGAMGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-59078139-A | — | — | None | — | — | JP | disclosed |
| US-20230346969-A1 | INTERMEDIATE FOR PREPARING ANTIBODY-DRUG CONJUGATE (ADC), PREPARATION METHOD THEREFOR, AND USE THEREOF | DARTSBIO PHARMACEUTICALS LTD. (CN) | 2023-11-02 | — | — | US | disclosed |
| US-11795320-B2 | Grafted polymer and use thereof | BAUSCH + LOMB IRELAND LIMITED (IE) | 2023-10-24 | — | — | US | disclosed |
| US-20180170812-A1 | METAL OXIDE CERAMIC NANOMATERIALS AND METHODS OF MAKING AND USING SAME | IVOCLAR VIVADENT AG (LI) | 2018-06-21 | — | — | US | disclosed |
| US-20180134717-A1 | PYRROLOBENZODIAZEPINES AND CONJUGATES THEREOF | SPIROGEN LIMITED (GB) | 2018-05-17 | — | — | US | disclosed |
| WO-2017205309-A1 | INSULIN RECEPTOR PARTIAL AGONISTS | MERCK SHARP & DOHME CORP. (US) | 2017-11-30 | — | — | WO | disclosed |
| WO-2017205191-A1 | INSULIN RECEPTOR PARTIAL AGONISTS AND GLP-1 ANALOGUES | MERCK SHARP & DOHME CORP. (US) | 2017-11-30 | — | — | WO | disclosed |
| US-9820917-B1 | Metal oxide ceramic nanomaterials and methods of making and using same | IVOCLAR VIVADENT AG (LI) | 2017-11-21 | — | — | US | disclosed |
| US-9822039-B1 | Metal oxide ceramic nanomaterials and methods of making and using same | IVOCLAR VIVADENT AG (LI) | 2017-11-21 | — | — | US | disclosed |
| US-9801944-B2 | Lipocationic polymers and uses thereof | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2017-10-31 | — | — | US | disclosed |
| US-9517270-B2 | Lipocationic polymers and uses thereof | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2016-12-13 | — | — | US | disclosed |
| US-20160310612-A1 | PEGYLATED DRUG-LINKERS FOR IMPROVED LIGAND-DRUG CONJUGATE PHARMACOKINETICS | SEATTLE GENETICS, INC. (US) | 2016-10-27 | — | — | US | disclosed |
| US-20160220681-A1 | LIPOCATIONIC POLYMERS AND USES THEREOF | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2016-08-04 | — | — | US | disclosed |
| US-20160220681-A1 | LIPOCATIONIC POLYMERS AND USES THEREOF | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2016-08-04 | — | — | US | disclosed |
| US-9394227-B1 | Treprostinil derivatives and compositions and uses thereof | Corsair Pharma, Inc. (US) | 2016-07-19 | — | — | US | disclosed |
| WO-2016081670-A2 | INSULIN RECEPTOR PARTIAL AGONISTS | MERCK SHARP & DOHME CORP. (US) | 2016-05-26 | — | — | WO | disclosed |
| US-20140142044-A1 | PEPTIDE MIMETIC LIGANDS OF POLO-LIKE KINASE 1 POLO BOX DOMAIN AND METHODS OF USE | The United States of America, as represented by the Secretary, Department of Health & Human Servic (US) | 2014-05-22 | — | — | US | disclosed |
| US-20070172422-A1 | Exponential pattern recognition based cellular targeting compositions, methods and anticancer applications | GLAZIER ARNOLD | 2007-07-26 | — | — | US | disclosed |
| US-20070154992-A1 | Compositions and methods for the preparation of protease resistant human growth hormone glycosylation mutants | NEOSE TECHNOLOGIES, INC. (US) | 2007-07-05 | — | — | US | disclosed |
| JP-S5978139-A | NOVEL KETO ETHER COMPOUND AND PREPARATION THEREOF | CHISSO CORP | 1984-05-04 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140142044-A1 | PEPTIDE MIMETIC LIGANDS OF POLO-LIKE KINASE 1 POLO BOX DOMAIN AND METHODS OF USE | PLK1, PLK4, PLK3 | ALDH1A1 4542/4885CA2 4262/4885LMNA 2211/4885 |
| US-20230346969-A1 | INTERMEDIATE FOR PREPARING ANTIBODY-DRUG CONJUGATE (ADC), PREPARATION METHOD THEREFOR, AND USE THEREOF | WEE1, THEM6, KIF11 | ALDH1A1 546/4885CA2 4566/4885LMNA 2954/4885 |
| US-20070172422-A1 | Exponential pattern recognition based cellular targeting compositions, methods and anticancer applications | EPHA2, EEA1, HAVCR2 | ALDH1A1 4187/4885CA2 2945/4885LMNA 4082/4885 |
| US-20180134717-A1 | PYRROLOBENZODIAZEPINES AND CONJUGATES THEREOF | HDAC10, PBDC1, PDCD10 | ALDH1A1 1192/4885CA2 4752/4885LMNA 2456/4885 |
| US-20160220681-A1 | LIPOCATIONIC POLYMERS AND USES THEREOF | NSUN3, METTL16, TRDMT1 | ALDH1A1 2579/4885CA2 4638/4885LMNA 156/4885 |
| US-20160310612-A1 | PEGYLATED DRUG-LINKERS FOR IMPROVED LIGAND-DRUG CONJUGATE PHARMACOKINETICS | EGFR, HDGF, CD47 | ALDH1A1 1001/4885CA2 4616/4885LMNA 155/4885 |
| US-20070154992-A1 | Compositions and methods for the preparation of protease resistant human growth hormone glycosylation mutants | GHITM, PTMS, GHRHR | ALDH1A1 4799/4885CA2 3991/4885LMNA 406/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.