Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 5/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.33 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.33 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.33 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.33 |
| ▸ | GBA1 | P04062 | 6/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MAN2B1 | O00754 | 1/20 | 0.32 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11501324 | 0.81 | ACE (0.37) | ACES1PR1S1PR3S1PR4ASAH1 | |
| SCHEMBL11036205 | 0.71 | MAN2B1 (0.35) | GBA1MAN2B1 | |
| SCHEMBL9800800 | 0.71 | MAN2B1 (0.39) | S1PR1S1PR3S1PR4GBA1MAN2B1 | |
| SCHEMBL11031751 | 0.70 | HCAR2 (0.40) | MAN2B1 | |
| SCHEMBL11031748 | 0.70 | HCAR2 (0.40) | MAN2B1 | |
| SCHEMBL9800830 | 0.69 | NAAA (0.34) | GBA1MAN2B1 | |
| SCHEMBL11237700 | 0.68 | MAN2B1 (0.36) | S1PR1S1PR3S1PR4GBA1MAN2B1 | |
| SCHEMBL10678300 | 0.68 | MAN2B1 (0.36) | S1PR1S1PR3S1PR4GBA1MAN2B1 | |
| SCHEMBL9800835 | 0.68 | FAAH (0.35) | GBA1MAN2B1 | |
| SCHEMBL10832279 | 0.68 | PLA2G2A (0.36) | ASAH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4534896-A | 3-Acylamino-2-oxoazetidine-1-(β-oxopropionic acid) | E. R. SQUIBB & SONS, INC. (US) | 1985-08-13 | — | — | US | disclosed |