Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | FABP7 | O15540 | 1/20 | 0.36 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 8/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 7/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.35 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.35 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27480438 | 0.89 | KIF11 (0.39) | KEAP1NFE2L2CHRM2CHRM3CYP2D6 | |
| SCHEMBL18324166 | 0.87 | SLC6A11 (0.43) | KCNH2KIF11CYP3A4SIGMAR1 | |
| SCHEMBL5883606 | 0.80 | KCNA3 (0.36) | KEAP1NFE2L2CHRM2CHRM3CYP2D6 | |
| SCHEMBL5883610 | 0.80 | KCNA3 (0.36) | KEAP1NFE2L2CHRM2CHRM3CYP2D6 | |
| SCHEMBL11006937 | 0.78 | SLC18A3 (0.47) | CYP2D6LMNAKIF11HRH1SIGMAR1 | |
| SCHEMBL18297952 | 0.77 | KEAP1 (0.35) | KEAP1NFE2L2FABP7FABP5CHRM2 | |
| SCHEMBL1355285 | 0.77 | CHRM3 (0.40) | KEAP1NFE2L2CHRM2CHRM3CYP2D6 | |
| SCHEMBL1355287 | 0.77 | KEAP1 (0.42) | KEAP1NFE2L2CHRM2CHRM3CYP2D6 | |
| SCHEMBL13280375 | 0.76 | SLC6A1 (0.44) | KEAP1NFE2L2CHRM3 | |
| SCHEMBL5091003 | 0.73 | TRPA1 (0.51) | CHRM2CHRM3CYP2D6KCNH2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-59230791-A | — | — | None | — | — | JP | disclosed |
| US-20150011749-A1 | USE OF CERTAIN METAL-ACCUMULATING PLANTS FOR THE PERFORMANCE OF ORGANIC CHEMISTRY REACTIONS | UNIVERSITE MONTPELLIER 2 SCIENCES ET TECHNIQUES (FR) | 2015-01-08 | — | — | US | disclosed |
| JP-S59230791-A | FIXED-TYPE THERMAL RECORDING MATERIAL | MITSUBISHI PAPER MILLS LTD | 1984-12-25 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150011749-A1 | USE OF CERTAIN METAL-ACCUMULATING PLANTS FOR THE PERFORMANCE OF ORGANIC CHEMISTRY REACTIONS | ME1, OSGEP, AGL | KEAP1 374/4885NFE2L2 858/4885FABP7 2285/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.