SCHEMBL1104248

SCHEMBL1104248

CCC(CO)(CO)COCCOC(=O)CCC(=O)O

nearest known ligand 0.46

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.46
DGKA P23743 1/20 0.36
ADRA2A P08913 1/20 0.34
ADRA1A P35348 1/20 0.34
MAPT P10636 1/20 0.33
BLM P54132 1/20 0.33
KDM6B O15054 1/20 0.33
KDM5C P41229 1/20 0.33
EGLN1 Q9GZT9 1/20 0.33
PHF8 Q9UPP1 1/20 0.33
KDM2A Q9Y2K7 1/20 0.33
LMNA P02545 1/20 0.32
TDP1 Q9NUW8 1/20 0.31
HSD17B10 Q99714 1/20 0.31
ALDH1A1 P00352 1/20 0.31
TSHR P16473 1/20 0.31
NPC1 O15118 1/20 0.31
HTR2C P28335 1/20 0.30
PAM P19021 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL542102 0.85 EGLN1 (0.38) THRBADRA2AADRA1AMAPTBLM
SCHEMBL1104235 0.84 ADRA2A (0.36) THRBDGKAADRA2AADRA1AMAPT
SCHEMBL6682544 0.82 MGLL (0.39) THRBDGKAADRA2AADRA1AMAPT
SCHEMBL13950722 0.79 THRB (0.37) THRBDGKAADRA2AADRA1AMAPT
SCHEMBL9074129 0.79 PAM (0.38) DGKATDP1HSD17B10ALDH1A1TSHR
SCHEMBL30477176 0.78 THRB (0.41) THRBADRA2AADRA1AMAPTBLM
SCHEMBL11669700 0.78 EPHX2 (0.45) THRBDGKAMAPTTDP1ALDH1A1
SCHEMBL8035913 0.77 THRB (0.47) THRBMAPTALDH1A1
SCHEMBL13933340 0.76 ADRA2A (0.33) DGKAADRA2AADRA1AMAPTBLM
SCHEMBL2306714 0.76 ALDH1A1 (0.54) THRBDGKAADRA2AADRA1AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8573765-B2 Active radiation curable ink composition, ink composition for inkjet recording, printed matter, and method of producing molded article of printed matter FUJIFILM CORPORATION (JP) 2013-11-05 US disclosed
US-8151705-B2 Method of preparing lithographic printing plate FUJIFILM CORPORATION (JP) 2012-04-10 US disclosed
US-20110241264-A1 ACTIVE RADIATION CURABLE INK COMPOSITION, INK COMPOSITION FOR INKJET RECORDING, PRINTED MATTER, AND METHOD OF PRODUCING MOLDED ARTICLE OF PRINTED MATTER FUJIFILM CORPORATION (JP) 2011-10-06 US disclosed
US-20100081771-A1 METHOD OF PREPARING LITHOGRAPHIC PRINTING PLATE FUJIFILM CORPORATION (JP) 2010-04-01 US disclosed
US-7645565-B2 Polymerizable composition and lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2010-01-12 US disclosed
US-20090053653-A1 POLYMERIZABLE COMPOSITION AND LITHOGRAPHIC PRINTING PLATE PRECURSOR FUJIFILM CORPORATION (JP) 2009-02-26 US disclosed
US-7491487-B2 Polymerizable composition and lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2009-02-17 US disclosed