Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.39 |
| ▸ | F12 | P00748 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30595067 | 1.00 | IDO1 (0.46) | IDO1MAPTALDH1A1RAB9ABLM | |
| SCHEMBL9128666 | 0.85 | IDO1 (0.41) | IDO1MAPTALDH1A1RAB9ABLM | |
| SCHEMBL8134553 | 0.82 | IDO1 (0.50) | IDO1MAPTALDH1A1RAB9ABLM | |
| SCHEMBL23533731 | 0.76 | CYP3A4 (0.37) | IDO1MAPTALDH1A1RAB9ABLM | |
| SCHEMBL29847372 | 0.76 | CYP3A4 (0.37) | IDO1MAPTALDH1A1RAB9ABLM | |
| SCHEMBL11212810 | 0.74 | ALDH1A1 (0.46) | MAPTALDH1A1RAB9ABLML3MBTL1 | |
| SCHEMBL1369794 | 0.74 | LMNA (0.50) | MAPTL3MBTL1LMNANUDT1KDM4E | |
| SCHEMBL11664265 | 0.74 | ALDH1A1 (0.46) | IDO1MAPTALDH1A1RAB9ABLM | |
| SCHEMBL30119859 | 0.74 | MAPT (0.50) | MAPTBLMLMNAKMT2ANUDT1 | |
| SCHEMBL1370432 | 0.74 | MAPT (0.50) | MAPTBLMLMNAKMT2ANUDT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 333 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2870140-A1 | TETRAHYDROQUINAZOLINONE DERIVATIVES AS PARP INHIBITORS | Lupin Limited (IN) | 2015-05-13 | — | — | EP | claimed |
| WO-2014009872-A1 | TETRAHYDROQUINAZOLINONE DERIVATIVES AS PARP INHIBITORS | LUPIN LIMITED (IN) | 2014-01-16 | — | — | WO | claimed |
| US-20030144263-A1 | Oxazolidinone derivatives, process for their preparation and pharmaceutical compositions containing them | SYNGENTA LIMITED (GB) | 2003-07-31 | — | — | US | claimed |
| JP-2073016-A | — | — | None | — | — | JP | disclosed |
| CN-110698485-B | Compound and application thereof | 北京鼎材科技有限公司 | 2025-03-04 | — | — | CN | disclosed |
| CN-110698485-B | Compound and application thereof | 北京鼎材科技有限公司 | 2025-03-04 | — | — | CN | disclosed |
| US-12022728-B2 | Organic electroluminescent element and electronic device | IDEMITSU KOSAN CO., LTD. (JP) | 2024-06-25 | — | — | US | disclosed |
| US-20230242556-A1 | NOVEL METHOD FOR MANUFACTURING DEUTERATED BORON COMPOUND | SFC CO., LTD. (KR) | 2023-08-03 | — | — | US | disclosed |
| US-11691983-B2 | Specifically substituted benzofuro- and benzothienoquinolines for organic light emitting diodes | IDEMITSU KOSAN CO., LTD. (JP) | 2023-07-04 | — | — | US | disclosed |
| US-11672172-B2 | Heterocyclic compound comprising aromatic amine group and organic light-emitting diode including the same | SFC CO., LTD. (KR) | 2023-06-06 | — | — | US | disclosed |
| US-11649430-B2 | Method to induce spore germination in fungi | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2023-05-16 | — | — | US | disclosed |
| US-4101553-A | Imidazo[2,1-a]isoquinolines | SANDOZ, INC. (US) | 1978-07-18 | — | — | US | disclosed |
| US-4101553-A | Imidazo[2,1-a]isoquinolines | SANDOZ, INC. (US) | 1978-07-18 | — | — | US | disclosed |
| US-4101553-A | Imidazo[2,1-a]isoquinolines | SANDOZ, INC. (US) | 1978-07-18 | — | — | US | disclosed |
| US-4100165-A | Imidazo [2,1-a]isoquinolines | SANDOZ, INC. (US) | 1978-07-11 | — | — | US | disclosed |
| US-4100165-A | Imidazo [2,1-a]isoquinolines | SANDOZ, INC. (US) | 1978-07-11 | — | — | US | disclosed |
| US-4093616-A | PYRROLO(1,2-A)PYRAZINIUM, PYRAZOLO(1,5-A)PYRIDINIUM, 1H-IMIDAZO(2,1-A)ISOQUINOLINIUM, OR IMIDAZO(5,1-A)ISOQUINOLINIUM SALTS | PFIZER INC. (US) | 1978-06-06 | — | — | US | disclosed |
| US-4093616-A | PYRROLO(1,2-A)PYRAZINIUM, PYRAZOLO(1,5-A)PYRIDINIUM, 1H-IMIDAZO(2,1-A)ISOQUINOLINIUM, OR IMIDAZO(5,1-A)ISOQUINOLINIUM SALTS | PFIZER INC. (US) | 1978-06-06 | — | — | US | disclosed |
| US-4044015-A | Imidazopyridinium compounds as hypoglycemic agents | PFIZER INC. (US) | 1977-08-23 | — | — | US | disclosed |
| US-4044015-A | Imidazopyridinium compounds as hypoglycemic agents | PFIZER INC. (US) | 1977-08-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030144263-A1 | Oxazolidinone derivatives, process for their preparation and pharmaceutical compositions containing them | CYP3A5, CYP2D6, OXA1L | IDO1 1888/4885MAPT 4796/4885ALDH1A1 3134/4885 |
| US-11691983-B2 | Specifically substituted benzofuro- and benzothienoquinolines for organic light emitting diodes | KCNQ2, KCNQ1, KCNQ4 | IDO1 3171/4885MAPT 611/4885ALDH1A1 865/4885 |
| US-11649430-B2 | Method to induce spore germination in fungi | ERG28, ETF1, DPM1 | IDO1 863/4885MAPT 3135/4885ALDH1A1 3690/4885 |
| US-20230242556-A1 | NOVEL METHOD FOR MANUFACTURING DEUTERATED BORON COMPOUND | BCL6B, BRD7, DBF4 | IDO1 2007/4885MAPT 1321/4885ALDH1A1 3057/4885 |
| US-12022728-B2 | Organic electroluminescent element and electronic device | L1CAM, ESR1, LEF1 | IDO1 2433/4885MAPT 1713/4885ALDH1A1 125/4885 |
| US-11672172-B2 | Heterocyclic compound comprising aromatic amine group and organic light-emitting diode including the same | DDC, TYR, AOC2 | IDO1 120/4885MAPT 241/4885ALDH1A1 208/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.