SCHEMBL1104837

SCHEMBL1104837

Cc1ccc2nc(-c3ccccn3)n(-c3ccccc3)c2c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DHFR P00374 2/20 0.48
NPC1 O15118 3/20 0.48
PKM P14618 2/20 0.48
RAB9A P51151 2/20 0.48
KDM4E B2RXH2 2/20 0.48
ALDH1A1 P00352 1/20 0.48
TP53 P04637 1/20 0.48
HPGD P15428 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
HSD17B10 Q99714 1/20 0.48
METAP2 P50579 1/20 0.47
METAP1 P53582 1/20 0.47
CBFB Q13951 1/20 0.47
HRH3 Q9Y5N1 4/20 0.44
CA12 O43570 1/20 0.43
CA9 Q16790 1/20 0.43
CTSD P07339 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
MAPK1 P28482 1/20 0.42
HTT P42858 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1104836 0.89 HRH3 (0.52) DHFRHRH3CA12CA9FGFR1
SCHEMBL19986452 0.89 MDM2 (0.45) DHFRNPC1PKMRAB9AKDM4E
SCHEMBL1104844 0.86 ALDH1A1 (0.48) DHFRNPC1PKMRAB9AKDM4E
SCHEMBL13376084 0.84 HTT (0.56) DHFRKDM4EALDH1A1HPGDHSD17B10
SCHEMBL1104842 0.81 ESR1 (0.55) NPC1RAB9AKDM4EALDH1A1TP53
SCHEMBL24953183 0.81 CTSD (0.47) DHFRPKMRAB9AKDM4EALDH1A1
SCHEMBL30172357 0.79 ESR2 (0.53) DHFRKDM4EALDH1A1HPGDHSD17B10
SCHEMBL1104864 0.79 ALDH1A1 (0.54) DHFRKDM4EALDH1A1MAPK1HTT
SCHEMBL25787082 0.79 KDM4E (0.51) KDM4EALDH1A1TP53HPGDSMN1; SMN2
SCHEMBL15999401 0.78 DHFR (0.47) DHFRHRH3CA12CA9PDE10A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 206 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220407018-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2022-12-22 US disclosed
US-11189809-B2 Organic EL device and display unit SONY CORPORATION (JP) 2021-11-30 US disclosed
US-11069862-B2 Material for organic electroluminescence device and organic electroluminescence device using the same IDEMITSU KOSAN CO., LTD. (JP) 2021-07-20 US disclosed
US-10411212-B2 Organic electroluminescent element IDEMITSU KOSAN CO., LTD. (JP) 2019-09-10 US disclosed
US-10026907-B2 Material for organic electroluminescence device and organic electroluminescence device using the same IDEMITSU KOSAN CO., LTD. (JP) 2018-07-17 US disclosed
US-10026907-B2 Material for organic electroluminescence device and organic electroluminescence device using the same IDEMITSU KOSAN CO., LTD. (JP) 2018-07-17 US disclosed
US-10020454-B2 Material for organic electroluminescence device and organic electroluminescence device using the same IDEMITSU KOSAN CO., LTD. (JP) 2018-07-10 US disclosed
US-10020454-B2 Material for organic electroluminescence device and organic electroluminescence device using the same IDEMITSU KOSAN CO., LTD. (JP) 2018-07-10 US disclosed
US-9954169-B2 Organic EL display and method of manufacturing the same JOLED INC. (JP) 2018-04-24 US disclosed
US-9954169-B2 Organic EL display and method of manufacturing the same JOLED INC. (JP) 2018-04-24 US disclosed
US-20090009066-A1 ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2009-01-08 US disclosed
US-20090009066-A1 ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2009-01-08 US disclosed
US-20090008607-A1 NAPHTHALENE DERIVATIVE, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE, AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2009-01-08 US disclosed
US-20090008607-A1 NAPHTHALENE DERIVATIVE, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE, AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2009-01-08 US disclosed
US-20080292904-A1 ORGANIC ELECTROLUMINESCENT DEVICE AND DISPLAY APPARATUS SONY CORPORATION (JP) 2008-11-27 US disclosed
US-20080292904-A1 ORGANIC ELECTROLUMINESCENT DEVICE AND DISPLAY APPARATUS SONY CORPORATION (JP) 2008-11-27 US disclosed
US-20080258613-A1 ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2008-10-23 US disclosed
US-20080258613-A1 ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2008-10-23 US disclosed
US-20080233387-A1 ORGANIC ELECTROLUMINESCENT DEVICE AND DISPLAY DEVICE SONY CORPORATION (JP) 2008-09-25 US disclosed
US-20080233387-A1 ORGANIC ELECTROLUMINESCENT DEVICE AND DISPLAY DEVICE SONY CORPORATION (JP) 2008-09-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090008607-A1 NAPHTHALENE DERIVATIVE, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE, AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME CCNL2, ARL1, CCNA1 DHFR 3928/4885NPC1 1659/4885PKM 2826/4885
US-11069862-B2 Material for organic electroluminescence device and organic electroluminescence device using the same EPCAM, ILK, PPOX DHFR 2840/4885NPC1 3774/4885PKM 2843/4885
US-10411212-B2 Organic electroluminescent element L1CAM, NES, EML4 DHFR 4635/4885NPC1 1505/4885PKM 1333/4885
US-20220407018-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME PPOX, EPCAM, STOM DHFR 3018/4885NPC1 4113/4885PKM 2106/4885
US-10020454-B2 Material for organic electroluminescence device and organic electroluminescence device using the same PPOX, EPCAM, STOM DHFR 3018/4885NPC1 4113/4885PKM 2106/4885
US-11189809-B2 Organic EL device and display unit L1CAM, ESR1, EPHA8 DHFR 4744/4885NPC1 1855/4885PKM 4427/4885
US-10026907-B2 Material for organic electroluminescence device and organic electroluminescence device using the same EPCAM, ILK, PPOX DHFR 2840/4885NPC1 3774/4885PKM 2843/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.