SCHEMBL11051157

SCHEMBL11051157

CS(=O)(=O)OS(c1ccccc1)(c1ccc(-c2ccccc2)cc1)c1ccc(-c2ccccc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 6/20 0.48
CA1 P00915 3/20 0.48
CA2 P00918 3/20 0.48
CA9 Q16790 2/20 0.48
CA12 O43570 1/20 0.48
MMP2 P08253 1/20 0.42
MMP7 P09237 1/20 0.42
MMP14 P50281 1/20 0.42
PTGS1 P23219 1/20 0.41
TSHR P16473 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
PARL Q9H300 1/20 0.41
ALDH1A1 P00352 1/20 0.41
GAA P10253 1/20 0.41
ADAMTS4 O75173 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11050731 0.91 SMN1; SMN2 (0.45) PTGS2CA1CA2CA9CA12
SCHEMBL207124 0.90 HTR6 (0.46) PTGS2CA1CA2CA9CA12
SCHEMBL4365042 0.85 HTT (0.49) CA1CA2CA9CA12SMN1; SMN2
SCHEMBL11052595 0.81 SOS1 (0.55) PTGS2CA1CA2CA9MMP2
SCHEMBL15063438 0.81 PKM (0.52) PTGS2CA1CA2MMP2SMN1; SMN2
SCHEMBL17557425 0.80 MMP13 (0.44) PTGS2MMP2PTGS1ALDH1A1
SCHEMBL7578519 0.80 ALDH1A1 (0.47) CA1CA2CA9TSHRSMN1; SMN2
SCHEMBL9155335 0.79 SOS1 (0.56) PTGS2CA1CA2CA9TSHR
SCHEMBL4643793 0.78 CA1 (0.46) PTGS2CA1CA2CA9CA12
SCHEMBL8320055 0.78 CA12 (0.36) PTGS2CA1CA2CA9CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4451408-A Process of preparing sulfonium organosulfonates THE DOW CHEMICAL COMPANY (US) 1984-05-29 US disclosed