SCHEMBL1105486

SCHEMBL1105486

CC(=O)c1ccc(N)nc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRP O00591 3/20 0.67
GABRD O14764 3/20 0.67
GABRA1 P14867 3/20 0.67
GABRB1 P18505 3/20 0.67
GABRG2 P18507 3/20 0.67
GABRB3 P28472 3/20 0.67
GABRA5 P31644 3/20 0.67
GABRA3 P34903 3/20 0.67
GABRA2 P47869 3/20 0.67
GABRB2 P47870 3/20 0.67
GABRA4 P48169 3/20 0.67
GABRE P78334 3/20 0.67
GABRA6 Q16445 3/20 0.67
GABRG1 Q8N1C3 3/20 0.67
GABRG3 Q99928 3/20 0.67
GABRQ Q9UN88 3/20 0.67
NNMT P40261 1/20 0.67
SMN1; SMN2 Q16637 1/20 0.67
HDAC1 Q13547 1/20 0.60
HDAC6 Q9UBN7 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL3426798 0.98 GABRP (0.64) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL16853374 0.82 GABRP (0.72) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL2281666 0.80 GABRP (0.63) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL2281669 0.80 GABRP (0.63) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL2027693 0.80 GABRP (1.00) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL29530489 0.80 GABRP (1.00) GABRPGABRDGABRA1GABRB1GABRG2
6-Aminonicotinamide SCHEMBL105510 0.80 NNMT (1.00) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL42011 0.80 GABRP (1.00) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL27636247 0.80 GABRP (0.63) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL2643250 0.79 GABRP (0.62) GABRPGABRDGABRA1GABRB1GABRG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 150 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115418642-B Copper-molybdenum etching solution and preparation method thereof 湖北兴福电子材料股份有限公司 2023-06-02 CN claimed
CN-115418642-A Copper-molybdenum etching solution and preparation method thereof 湖北兴福电子材料股份有限公司 2022-12-02 CN claimed
EP-1654260-A4 6-MENBERED HETEROARYL COMPOUNDS FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS PFIZER PROD INC (US) 2008-09-24 EP claimed
EP-1654260-A2 6-MENBERED HETEROARYL COMPOUNDS FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS Pfizer Products Inc. (US) 2006-05-10 EP claimed
US-20050107381-A1 6-membered heteroaryl compounds for the treatment of neurodegenerative disorders PFIZER, INC. 2005-05-19 US claimed
WO-2005011601-A2 6-MENBERED HETEROARYL COMPOUNDS FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS PFIZER PRODUCTS, INC. (US) 2005-02-10 WO claimed
CN-121796667-B Antibacterial suture line for surgical suture and preparation method thereof 上海天清生物材料有限公司 2026-05-08 CN disclosed
EP-4719394-A2 INHIBITORS OF TYK2 Atomwise Inc. (US) 2026-04-08 EP disclosed
CN-121796667-A Antibacterial suture line for surgical suture and preparation method thereof 上海天清生物材料有限公司 2026-04-07 CN disclosed
US-20260048051-A1 TREATMENT OF INFLAMMATORY BOWEL DISEASE ATOMWISE INC (US) 2026-02-19 US disclosed
US-20250388577-A1 METTL3 INHIBITORY COMPOUNDS STORM THERAPEUTICS LTD (GB) 2025-12-25 US disclosed
WO-2025235363-A1 CYCLIN-DEPENDENT KINASE 4 DEGRADERS BLUEPRINT MEDICINES CORPORATION (US) 2025-11-13 WO disclosed
WO-2025226545-A1 MODULATORS OF MITOCHONDRIAL DNA REPLICATION PRETZEL THERAPEUTICS, INC. (US) 2025-10-30 WO disclosed
US-20050107381-A1 6-membered heteroaryl compounds for the treatment of neurodegenerative disorders PFIZER, INC. 2005-05-19 US disclosed
WO-2005011601-A2 6-MENBERED HETEROARYL COMPOUNDS FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS PFIZER PRODUCTS, INC. (US) 2005-02-10 WO disclosed
US-20030144326-A1 Cyclic amine phenyl beta-3 adrenergic receptor agonists WYETH 2003-07-31 US disclosed
EP-1301482-A1 CYCLIC AMINE PHENYL BETA-3 ADRENERGIC RECEPTOR AGONISTS Wyeth (US) 2003-04-16 EP disclosed
US-6525202-B2 E.g., substituted (4-amino-5-hydroxyphenyl)-oxy-)piperidinyl thiazolidin-2,4-dione; antidiabetic agents; atherosclerosis, gastrointestinal, metabolic disorders, glaucoma, neurogenetic inflammation, ocular hypertension and frequent urination WYETH 2003-02-25 US disclosed
US-20020028835-A1 Cyclic amine phenyl beta-3 adrenergic receptor agonists WYETH 2002-03-07 US disclosed
WO-2002006232-A1 CYCLIC AMINE PHENYL BETA-3 ADRENERGIC RECEPTOR AGONISTS WYETH (US) 2002-01-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030144326-A1 Cyclic amine phenyl beta-3 adrenergic receptor agonists ADRB1, ADRB3, ADRB2 GABRP 973/4885GABRD 3349/4885GABRA1 1563/4885
US-20260048051-A1 TREATMENT OF INFLAMMATORY BOWEL DISEASE TYK2, FRK, DYRK2 GABRP 2796/4885GABRD 2921/4885GABRA1 1556/4885
US-20050107381-A1 6-membered heteroaryl compounds for the treatment of neurodegenerative disorders APP, BACE1, SNCA GABRP 3200/4885GABRD 3942/4885GABRA1 2513/4885
US-20250388577-A1 METTL3 INHIBITORY COMPOUNDS METTL3, RNMT, TPMT GABRP 4746/4885GABRD 4566/4885GABRA1 4204/4885
US-20020028835-A1 Cyclic amine phenyl beta-3 adrenergic receptor agonists ADRB1, ADRB3, ADRB2 GABRP 973/4885GABRD 3349/4885GABRA1 1563/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.