Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.31 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.31 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.31 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.31 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.31 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.31 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.31 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.31 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11061474 | 0.91 | L3MBTL1 (0.34) | MEN1KMT2AL3MBTL1CYP1A2CYP3A4 | |
| SCHEMBL10959341 | 0.78 | L3MBTL1 (0.37) | MEN1KMT2AL3MBTL1CYP1A2CYP3A4 | |
| SCHEMBL11060716 | 0.78 | MEN1 (0.36) | MEN1KMT2ACYP3A4MAPTMAPK8 | |
| SCHEMBL11058186 | 0.77 | ALDH1A1 (0.33) | L3MBTL1CYP1A2CYP3A4GLAMAPT | |
| SCHEMBL11059945 | 0.75 | HTT (0.35) | KMT2AL3MBTL1CYP1A2CYP3A4GLA | |
| SCHEMBL11064903 | 0.74 | L3MBTL1 (0.37) | L3MBTL1CYP1A2CYP3A4GLAMAPT | |
| SCHEMBL11058744 | 0.73 | MEN1 (0.33) | MEN1KMT2AL3MBTL1CYP1A2MAPT | |
| SCHEMBL11065726 | 0.72 | XDH (0.37) | MEN1KMT2ACYP3A4MAPTMAPK8 | |
| SCHEMBL10959912 | 0.69 | MAPT (0.36) | MEN1KMT2AL3MBTL1MAPTALDH1A1 | |
| SCHEMBL11065100 | 0.69 | MEN1 (0.35) | MEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4434167-A | Pyrimidyl thioureas useful for the treatment of hypertension and hyperlipidemia | BEIERSDORF AKTIENGESELLSCHAFT (DE) | 1984-02-28 | — | — | US | disclosed |