Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPOR | P19235 | 1/20 | 0.34 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 4/20 | 0.33 |
| ▸ | MAOA | P21397 | 4/20 | 0.33 |
| ▸ | MAOB | P27338 | 4/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11071446 | 0.85 | ALDH1A1 (0.38) | EPORTRPV3P2RX3ACHEMEN1 | |
| SCHEMBL11066972 | 0.84 | ALDH1A1 (0.36) | EPORTRPV3P2RX3ACHEMEN1 | |
| SCHEMBL11070976 | 0.81 | TRPV3 (0.38) | TRPV3P2RX3ACHEMEN1ALDH1A1 | |
| SCHEMBL11062094 | 0.78 | KCNH2 (0.38) | TRPV3P2RX3ALDH1A1KCNH2PTGS1 | |
| SCHEMBL11065707 | 0.76 | ADAMTS4 (0.39) | TRPV3P2RX3MEN1ALDH1A1KMT2A | |
| SCHEMBL11275809 | 0.75 | ALDH1A1 (0.47) | ALDH1A1KCNH2 | |
| SCHEMBL11478773 | 0.75 | ADAMTS4 (0.39) | TRPV3P2RX3MEN1ALDH1A1KMT2A | |
| SCHEMBL11460618 | 0.74 | ALOX5 (0.40) | PTGS1SLC6A2LMNA | |
| SCHEMBL11072017 | 0.74 | ADAMTS4 (0.38) | TRPV3P2RX3MEN1ALDH1A1KMT2A | |
| SCHEMBL11069125 | 0.73 | ADAMTS4 (0.38) | TRPV3P2RX3MEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4447613-A | Pyridyl esters and thiolesters of aminoalkanoic acids | ZOECON CORPORATION (US) | 1984-05-08 | — | — | US | disclosed |
| US-4247701-A | Certain pesticidal substituted amino lower-alkanoates or lower-alkano-thioates containing pyridyl in the ester portion | ZOECON CORPORATION (US) | 1981-01-27 | — | — | US | disclosed |