Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | TACR2 | P21452 | 1/20 | 0.41 |
| ▸ | TACR1 | P25103 | 1/20 | 0.41 |
| ▸ | TACR3 | P29371 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10567416 | 0.81 | SIGMAR1 (0.54) | SIGMAR1HRH3DRD2DRD4DRD3 | |
| SCHEMBL11067562 | 0.78 | HTR7 (0.53) | HTR7MAPTGAADRD2DRD4 | |
| SCHEMBL11070246 | 0.78 | DRD4 (0.55) | SIGMAR1HRH3DRD2DRD4DRD3 | |
| SCHEMBL11064993 | 0.76 | HTR7 (0.51) | HTR7TACR2TACR1TACR3MAPT | |
| SCHEMBL11072709 | 0.75 | MEN1 (0.47) | HTR7SIGMAR1HRH3DRD2DRD3 | |
| SCHEMBL11065111 | 0.73 | SIGMAR1 (0.53) | HTR7SIGMAR1DRD2DRD4DRD3 | |
| SCHEMBL11066815 | 0.73 | ABCB1 (0.52) | GAA | |
| SCHEMBL11071804 | 0.73 | HTR7 (0.53) | HTR7MAPTGAADRD2DRD4 | |
| SCHEMBL11070828 | 0.71 | OPRL1 (0.47) | TACR1SIGMAR1 | |
| SCHEMBL11362472 | 0.71 | HTR6 (0.41) | GAADRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4482560-A | Carbostyril derivatives, and antihistaminic agents containing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-11-13 | — | — | US | disclosed |