Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN1A | P35498 | 2/20 | 0.41 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 2/20 | 0.34 |
| ▸ | ADAMTS5 | Q9UNA0 | 3/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.32 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11066967 | 0.77 | SCN1A (0.55) | SCN1ASCN5ASCN9AADRB2ADRB1 | |
| SCHEMBL11073435 | 0.74 | HTR7 (0.48) | SCN1ASCN5ASCN9AHRH3HTR7 | |
| Hydrochloric Acid SCHEMBL11070539 | 0.73 | HTR7 (0.47) | SCN1ASCN5ASCN9AHRH3HTR7 | |
| SCHEMBL11061316 | 0.73 | SCN5A (0.69) | SCN1ASCN5ASCN9AADRB2ADRB1 | |
| SCHEMBL11068088 | 0.71 | SCN1A (0.45) | SCN1ASCN5ASCN9APARP1ADAMTS5 | |
| Iodide SCHEMBL11068796 | 0.70 | SLC18A3 (0.45) | SCN1ASCN5ASCN9AADRB2ADRB1 | |
| Iodide SCHEMBL11065747 | 0.69 | ADRB1 (0.54) | SCN1ASCN5ASCN9AADRB2ADRB1 | |
| SCHEMBL9653563 | 0.68 | ADRB1 (0.49) | SCN1ASCN5ASCN9AADRB2ADRB1 | |
| SCHEMBL10837771 | 0.67 | SIGMAR1 (0.52) | HTR1AKCNH2PARP1HTR7 | |
| SCHEMBL10572425 | 0.67 | HTR1A (0.43) | SCN1ASCN5ASCN9AADRB2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4482560-A | Carbostyril derivatives, and antihistaminic agents containing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-11-13 | — | — | US | disclosed |