Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 5/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.40 |
| ▸ | PTGES | O14684 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11067069 | 0.80 | PDE7A (0.45) | ALDH1A1LMNAHTTRAB9ASMN1; SMN2 | |
| SCHEMBL8564485 | 0.77 | LMNA (0.61) | ALDH1A1LMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL11404352 | 0.74 | ALDH1A1 (0.52) | ALDH1A1LMNAHTTSMN1; SMN2MEN1 | |
| SCHEMBL347599 | 0.74 | HSPB1 (0.53) | ALDH1A1LMNAHTTRAB9ASMN1; SMN2 | |
| SCHEMBL11064622 | 0.71 | TXNRD1 (0.62) | ALDH1A1LMNAHTTRAB9ASMN1; SMN2 | |
| SCHEMBL7228750 | 0.71 | MAPT (0.61) | LMNARAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL11067211 | 0.70 | HSD17B10 (0.47) | ALDH1A1HTTGAAHSPB1 | |
| SCHEMBL27286335 | 0.69 | ALDH1A1 (0.63) | ALDH1A1LMNAHTTRAB9AMEN1 | |
| SCHEMBL11805291 | 0.69 | TXNRD1 (0.58) | ALDH1A1LMNAHTTRAB9AMEN1 | |
| SCHEMBL18476534 | 0.69 | ALOX5 (0.47) | ALDH1A1LMNAHTTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4275077-A | Insecticidal acyl urea derivatives | CELAMERCK GMBH & CO. KG (DE) | 1981-06-23 | — | — | US | disclosed |