Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 5/20 | 0.48 |
| ▸ | HTR7 | P34969 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11065358 | 0.97 | TSHR (0.49) | HTR1AHTR7ALDH1A1LMNAHTT | |
| SCHEMBL10601141 | 0.84 | PDE10A (0.55) | HTR1AHTR7ALDH1A1HTTTSHR | |
| SCHEMBL11060823 | 0.83 | TLR8 (0.54) | HTR1AHTR7ALDH1A1LMNASIGMAR1 | |
| SCHEMBL11073097 | 0.82 | ALDH1A1 (0.47) | HTR1AHTR7ALDH1A1LMNAHTT | |
| SCHEMBL11059735 | 0.80 | SIGMAR1 (0.53) | HTR1AHTR7ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL10602407 | 0.80 | HTR1A (0.44) | HTR1AHTR7ALDH1A1HTTSIGMAR1 | |
| SCHEMBL11282844 | 0.80 | PDE10A (0.53) | HTR1AHTR7SIGMAR1DRD2DRD3 | |
| SCHEMBL11073093 | 0.79 | ALDH1A1 (0.46) | HTR1AHTR7ALDH1A1LMNAHTT | |
| SCHEMBL11073089 | 0.78 | PDE10A (0.48) | HTR1AHTR7ALDH1A1LMNAHTT | |
| SCHEMBL11069700 | 0.77 | HTR7 (0.57) | HTR1AHTR7ALDH1A1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4461894-A | Naphth[1,2-d]imidazoles | GRUPPO LEPETIT S.P.A. (IT) | 1984-07-24 | — | — | US | disclosed |
| US-4360674-A | Naphth[1,2-d]imidazoles | GRUPPO LEPETIT S.P.A. (IT) | 1982-11-23 | — | — | US | disclosed |