SCHEMBL1107787

SCHEMBL1107787

O=C(Oc1ccccc1)C12CC3(c4ccccc4)CC(c4ccccc4)(C1)CC(c1ccccc1)(C2)C3

nearest known ligand 0.40

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 1/20 0.40
L3MBTL1 Q9Y468 2/20 0.39
POLB P06746 1/20 0.39
MAPT P10636 2/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
GAA P10253 1/20 0.39
XBP1 P17861 1/20 0.39
LMNA P02545 2/20 0.39
KDM4E B2RXH2 2/20 0.38
TDP1 Q9NUW8 2/20 0.38
ALDH1A1 P00352 2/20 0.37
ATM Q13315 1/20 0.37
HPGD P15428 1/20 0.36
ALOX15 P16050 1/20 0.36
HSD17B10 Q99714 1/20 0.36
RAB9A P51151 1/20 0.35
AKR1C1 Q04828 1/20 0.34
NSD2 O96028 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5078650 0.85 MAPT (0.46) L3MBTL1POLBMAPTMEN1KMT2A
SCHEMBL5081791 0.80 MAPT (0.42) HSD11B1L3MBTL1POLBMAPTGAA
SCHEMBL5084629 0.80 MAPT (0.42) HSD11B1L3MBTL1POLBMAPTGAA
SCHEMBL5082335 0.80 MAPT (0.42) HSD11B1L3MBTL1POLBMAPTGAA
SCHEMBL17468122 0.79 MEN1 (0.57) HSD11B1MEN1KMT2AGAALMNA
SCHEMBL14651305 0.79 HSD11B1 (0.59) HSD11B1POLBMAPTMEN1KMT2A
SCHEMBL1107786 0.77 MEN1 (0.41) HSD11B1MEN1KMT2ALMNATDP1
SCHEMBL13618742 0.75 LMNA (0.33) HSD11B1MEN1KMT2ALMNAALDH1A1
SCHEMBL17467926 0.75 AKR1C1 (0.47) HSD11B1MEN1KMT2ALMNAALDH1A1
SCHEMBL5082277 0.75 MAPT (0.53) L3MBTL1POLBMAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3389110-B1 ORGANIC ELECTROLUMINESCENT ELEMENT UDC IRELAND LTD (IE) 2023-12-27 EP disclosed
US-11832508-B2 Organic electroluminescence device UDC IRELAND LIMITED (IE) 2023-11-28 US disclosed
US-11832508-B2 Organic electroluminescence device UDC IRELAND LIMITED (IE) 2023-11-28 US disclosed
US-20200243777-A1 ORGANIC ELECTROLUMINESCENCE DEVICE UDC IRELAND LTD (IE) 2020-07-30 US disclosed
US-10629828-B2 Organic electroluminescence device UDC IRELAND LIMITED (IE) 2020-04-21 US disclosed
US-10403832-B2 Organic electroluminescence device UDC IRELAND LIMITED (IE) 2019-09-03 US disclosed
US-9461253-B2 Organic electroluminescence device and luminescence apparatus UDC IRELAND LIMITED (IE) 2016-10-04 US disclosed
US-9461253-B2 Organic electroluminescence device and luminescence apparatus UDC IRELAND LIMITED (IE) 2016-10-04 US disclosed
US-9340728-B2 Organic electroluminescence device UDC IRELAND LIMITED (IE) 2016-05-17 US disclosed
US-9340728-B2 Organic electroluminescence device UDC IRELAND LIMITED (IE) 2016-05-17 US disclosed
US-20100171417-A1 CHARGE TRANSPORT MATERIAL AND ORGANIC ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION (JP) 2010-07-08 US disclosed
US-20100171418-A1 ORGANIC ELECTROLUMINESCENT DEVICE FUJIFILM CORPORATION (JP) 2010-07-08 US disclosed
US-20100140605-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND LUMINESCENCE APPARATUS FUJIFILM CORPORATION (JP) 2010-06-10 US disclosed
US-20100140605-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND LUMINESCENCE APPARATUS FUJIFILM CORPORATION (JP) 2010-06-10 US disclosed
US-20090267500-A1 ORGANIC ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION (JP) 2009-10-29 US disclosed
US-20090267500-A1 ORGANIC ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION (JP) 2009-10-29 US disclosed
US-20090218936-A1 Organic electroluminescence element FUJIFILM CORPORATION (JP) 2009-09-03 US disclosed
US-20090218936-A1 Organic electroluminescence element FUJIFILM CORPORATION (JP) 2009-09-03 US disclosed
US-20090218935-A1 Organic electroluminescence element FUJIFILM CORPORATION (JP) 2009-09-03 US disclosed
US-20090218935-A1 Organic electroluminescence element FUJIFILM CORPORATION (JP) 2009-09-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100171417-A1 CHARGE TRANSPORT MATERIAL AND ORGANIC ELECTROLUMINESCENCE DEVICE L1CAM, SLC67A1, SLC26A3 HSD11B1 4539/4885L3MBTL1 735/4885POLB 2202/4885
US-20200243777-A1 ORGANIC ELECTROLUMINESCENCE DEVICE L1CAM, APOL1, MT-ND4L HSD11B1 4222/4885L3MBTL1 405/4885POLB 1789/4885
US-11832508-B2 Organic electroluminescence device LAGE3, L1CAM, LEF1 HSD11B1 3048/4885L3MBTL1 604/4885POLB 1815/4885
US-10403832-B2 Organic electroluminescence device LAGE3, L1CAM, LEF1 HSD11B1 3116/4885L3MBTL1 589/4885POLB 1692/4885
US-10629828-B2 Organic electroluminescence device L1CAM, APOL1, MT-ND4L HSD11B1 4222/4885L3MBTL1 405/4885POLB 1789/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.