SCHEMBL1107786

SCHEMBL1107786

CC(C)(C)OC(=O)C12CC3(c4ccccc4)CC(c4ccccc4)(C1)CC(c1ccccc1)(C2)C3

nearest known ligand 0.41

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
LMNA P02545 2/20 0.37
ALDH1A1 P00352 2/20 0.36
RORC P51449 2/20 0.36
HSD11B1 P28845 1/20 0.35
TSHR P16473 3/20 0.35
ALOX15 P16050 1/20 0.35
ATM Q13315 1/20 0.35
CYP17A1 P05093 2/20 0.35
CYP19A1 P11511 2/20 0.35
HSD17B10 Q99714 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
GPR119 Q8TDV5 1/20 0.34
USP30 Q70CQ3 1/20 0.34
HTT P42858 1/20 0.33
OPRM1 P35372 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17468122 0.80 MEN1 (0.57) MEN1KMT2ALMNAALDH1A1HSD11B1
SCHEMBL30722350 0.79 RXRA (0.44) LMNA
SCHEMBL1107787 0.77 HSD11B1 (0.40) MEN1KMT2ALMNAALDH1A1HSD11B1
SCHEMBL21238259 0.75 DPP8 (0.43) MEN1KMT2ATSHRALOX15ATM
SCHEMBL12832155 0.74 LMNA (0.37) MEN1KMT2ALMNAALDH1A1HSD11B1
SCHEMBL5080852 0.74 DGAT1 (0.36) MEN1KMT2ACYP17A1CYP19A1
SCHEMBL30934615 0.73 OPRM1 (0.42) MEN1KMT2ALMNAALDH1A1HSD11B1
SCHEMBL31524106 0.73 CA1 (0.43) MEN1KMT2AALOX15TDP1HTT
SCHEMBL17467926 0.73 AKR1C1 (0.47) MEN1KMT2ALMNAALDH1A1HSD11B1
SCHEMBL9774955 0.72 MEN1 (0.38) MEN1KMT2AALDH1A1RORCTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11832508-B2 Organic electroluminescence device UDC IRELAND LIMITED (IE) 2023-11-28 US disclosed
US-11832508-B2 Organic electroluminescence device UDC IRELAND LIMITED (IE) 2023-11-28 US disclosed
US-20200243777-A1 ORGANIC ELECTROLUMINESCENCE DEVICE UDC IRELAND LTD (IE) 2020-07-30 US disclosed
US-10629828-B2 Organic electroluminescence device UDC IRELAND LIMITED (IE) 2020-04-21 US disclosed
US-10403832-B2 Organic electroluminescence device UDC IRELAND LIMITED (IE) 2019-09-03 US disclosed
US-9461253-B2 Organic electroluminescence device and luminescence apparatus UDC IRELAND LIMITED (IE) 2016-10-04 US disclosed
US-9461253-B2 Organic electroluminescence device and luminescence apparatus UDC IRELAND LIMITED (IE) 2016-10-04 US disclosed
EP-2113548-B1 ORGANIC ELECTROLUMINESCENCE DEVICE UDC IRELAND LTD (IE) 2016-05-25 EP disclosed
US-9340728-B2 Organic electroluminescence device UDC IRELAND LIMITED (IE) 2016-05-17 US disclosed
US-9340728-B2 Organic electroluminescence device UDC IRELAND LIMITED (IE) 2016-05-17 US disclosed
US-20100171418-A1 ORGANIC ELECTROLUMINESCENT DEVICE FUJIFILM CORPORATION (JP) 2010-07-08 US disclosed
US-20100140605-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND LUMINESCENCE APPARATUS FUJIFILM CORPORATION (JP) 2010-06-10 US disclosed
US-20100140605-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND LUMINESCENCE APPARATUS FUJIFILM CORPORATION (JP) 2010-06-10 US disclosed
EP-2113548-A1 Organic electroluminescence device FUJIFILM Corporation (JP) 2009-11-04 EP disclosed
US-20090267500-A1 ORGANIC ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION (JP) 2009-10-29 US disclosed
US-20090267500-A1 ORGANIC ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION (JP) 2009-10-29 US disclosed
US-20090218936-A1 Organic electroluminescence element FUJIFILM CORPORATION (JP) 2009-09-03 US disclosed
US-20090218936-A1 Organic electroluminescence element FUJIFILM CORPORATION (JP) 2009-09-03 US disclosed
US-20090218935-A1 Organic electroluminescence element FUJIFILM CORPORATION (JP) 2009-09-03 US disclosed
US-20090218935-A1 Organic electroluminescence element FUJIFILM CORPORATION (JP) 2009-09-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200243777-A1 ORGANIC ELECTROLUMINESCENCE DEVICE L1CAM, APOL1, MT-ND4L MEN1 2882/4885KMT2A 3128/4885LMNA 2148/4885
US-11832508-B2 Organic electroluminescence device LAGE3, L1CAM, LEF1 MEN1 869/4885KMT2A 2284/4885LMNA 955/4885
US-10403832-B2 Organic electroluminescence device LAGE3, L1CAM, LEF1 MEN1 845/4885KMT2A 2328/4885LMNA 960/4885
US-10629828-B2 Organic electroluminescence device L1CAM, APOL1, MT-ND4L MEN1 2882/4885KMT2A 3128/4885LMNA 2148/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.