SCHEMBL1107798

SCHEMBL1107798

c1ccc(OC23CC4(c5ccccc5)CC(c5ccccc5)(C2)CC(c2ccccc2)(C3)C4)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PNMT P11086 1/20 0.38
GAA P10253 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
GRIN2D O15399 1/20 0.34
GRIN3B O60391 1/20 0.34
GRIN1 Q05586 1/20 0.34
GRIN2A Q12879 1/20 0.34
GRIN2B Q13224 1/20 0.34
GRIN2C Q14957 1/20 0.34
GRIN3A Q8TCU5 1/20 0.34
LTA4H P09960 1/20 0.33
TSHR P16473 1/20 0.33
MAOA P21397 1/20 0.31
MAOB P27338 1/20 0.31
CA4 P22748 1/20 0.31
OPRM1 P35372 2/20 0.31
OPRL1 P41146 2/20 0.31
HTR1A P08908 1/20 0.31
SLC6A2 P23975 1/20 0.31
SLC6A4 P31645 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30555211 0.79 PNMT (0.52) PNMTGRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL3973946 0.79 PNMT (0.52) PNMTGRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL2710992 0.72 PNMT (0.46) PNMTGRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL12908018 0.69 PNMT (0.43) PNMTGRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL1107820 0.69 PNMT (0.43) PNMTGRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL1107788 0.69 MAOB (0.45) PNMTGRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL1107787 0.68 HSD11B1 (0.40) GAAMEN1KMT2A
SCHEMBL21042136 0.67 PNMT (0.41) PNMTGRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL19830978 0.67 PNMT (0.41) PNMTGRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL26633327 0.67 PNMT (0.38) PNMTNPSR1GRIN2DGRIN3BGRIN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11832508-B2 Organic electroluminescence device UDC IRELAND LIMITED (IE) 2023-11-28 US disclosed
US-11832508-B2 Organic electroluminescence device UDC IRELAND LIMITED (IE) 2023-11-28 US disclosed
US-20200243777-A1 ORGANIC ELECTROLUMINESCENCE DEVICE UDC IRELAND LTD (IE) 2020-07-30 US disclosed
US-10629828-B2 Organic electroluminescence device UDC IRELAND LIMITED (IE) 2020-04-21 US disclosed
US-10403832-B2 Organic electroluminescence device UDC IRELAND LIMITED (IE) 2019-09-03 US disclosed
US-9461253-B2 Organic electroluminescence device and luminescence apparatus UDC IRELAND LIMITED (IE) 2016-10-04 US disclosed
US-9461253-B2 Organic electroluminescence device and luminescence apparatus UDC IRELAND LIMITED (IE) 2016-10-04 US disclosed
EP-2113548-B1 ORGANIC ELECTROLUMINESCENCE DEVICE UDC IRELAND LTD (IE) 2016-05-25 EP disclosed
US-9340728-B2 Organic electroluminescence device UDC IRELAND LIMITED (IE) 2016-05-17 US disclosed
US-9340728-B2 Organic electroluminescence device UDC IRELAND LIMITED (IE) 2016-05-17 US disclosed
US-20100171417-A1 CHARGE TRANSPORT MATERIAL AND ORGANIC ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION (JP) 2010-07-08 US disclosed
US-20100140605-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND LUMINESCENCE APPARATUS FUJIFILM CORPORATION (JP) 2010-06-10 US disclosed
US-20100140605-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND LUMINESCENCE APPARATUS FUJIFILM CORPORATION (JP) 2010-06-10 US disclosed
EP-2113548-A1 Organic electroluminescence device FUJIFILM Corporation (JP) 2009-11-04 EP disclosed
US-20090267500-A1 ORGANIC ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION (JP) 2009-10-29 US disclosed
US-20090267500-A1 ORGANIC ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION (JP) 2009-10-29 US disclosed
US-20090218936-A1 Organic electroluminescence element FUJIFILM CORPORATION (JP) 2009-09-03 US disclosed
US-20090218936-A1 Organic electroluminescence element FUJIFILM CORPORATION (JP) 2009-09-03 US disclosed
US-20090218935-A1 Organic electroluminescence element FUJIFILM CORPORATION (JP) 2009-09-03 US disclosed
US-20090218935-A1 Organic electroluminescence element FUJIFILM CORPORATION (JP) 2009-09-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100171417-A1 CHARGE TRANSPORT MATERIAL AND ORGANIC ELECTROLUMINESCENCE DEVICE L1CAM, SLC67A1, SLC26A3 PNMT 1155/4885GAA 2793/4885NPSR1 1672/4885
US-20200243777-A1 ORGANIC ELECTROLUMINESCENCE DEVICE L1CAM, APOL1, MT-ND4L PNMT 236/4885GAA 2203/4885NPSR1 4119/4885
US-11832508-B2 Organic electroluminescence device LAGE3, L1CAM, LEF1 PNMT 2335/4885GAA 1954/4885NPSR1 4731/4885
US-10403832-B2 Organic electroluminescence device LAGE3, L1CAM, LEF1 PNMT 2329/4885GAA 1883/4885NPSR1 4732/4885
US-10629828-B2 Organic electroluminescence device L1CAM, APOL1, MT-ND4L PNMT 236/4885GAA 2203/4885NPSR1 4119/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.